Vasopressin-neurophysin 2-copeptin
Intermolecular
Cysteine 110 and cysteine 110
Cysteine 110 and cysteine 105
Intramolecular
Cysteine 20 and cysteine 25
Cysteine 41 and cysteine 85
Cysteine 98 and cysteine 116
Cysteine 92 and cysteine 116
Cysteine 52 and cysteine 75
Cysteine 92 and cysteine 104
Cysteine 59 and cysteine 65
Cysteine 44 and cysteine 58
More...Cysteine 44 and cysteine 75
Cysteine 92 and cysteine 98
Cysteine 44 and cysteine 52
Cysteine 59 and cysteine 105
Cysteine 65 and cysteine 105
Cysteine 104 and cysteine 116
Cysteine 65 and cysteine 110
Cysteine 59 and cysteine 110
Cysteine 58 and cysteine 75
Cysteine 98 and cysteine 104
Cysteine 41 and cysteine 52
Cysteine 52 and cysteine 58
Cysteine 105 and cysteine 116
Cysteine 41 and cysteine 75
Cysteine 104 and cysteine 105
Cysteine 92 and cysteine 105
Cysteine 44 and cysteine 59
Cysteine 58 and cysteine 59
Cysteine 52 and cysteine 85
Cysteine 41 and cysteine 44
Cysteine 59 and cysteine 75
Cysteine 75 and cysteine 85
Cysteine 92 and cysteine 110
Cysteine 65 and cysteine 116
Cysteine 98 and cysteine 105
Cysteine 104 and cysteine 110
Cysteine 110 and cysteine 116
Cysteine 44 and cysteine 65
Cysteine 58 and cysteine 65
Cysteine 52 and cysteine 59
Cysteine 59 and cysteine 92
Cysteine 65 and cysteine 92
Cysteine 58 and cysteine 105
Cysteine 59 and cysteine 104
Cysteine 65 and cysteine 104
Cysteine 58 and cysteine 110
1npo A 79 C 79
A redox-regulated disulphide may form between two units of Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.8381538
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.8381538
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.8381538
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.8381538
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.972913
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.972913
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.972913
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.972913
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.074653
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.074653
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.074653
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.074653
seq distance
6
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.0793557
seq distance
43
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.0793557
seq distance
43
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1468577
seq distance
43
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1468577
seq distance
43
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.193982
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.193982
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.193982
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.193982
seq distance
6
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.444616
seq distance
11
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.444616
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8018527
seq distance
51
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8018527
seq distance
51
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8018527
seq distance
51
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8018527
seq distance
51
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8414574
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8414574
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8414574
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8414574
seq distance
51
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
7.0169873
seq distance
11
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
7.0169873
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.358712
seq distance
52
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.358712
seq distance
52
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.442004
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.442004
seq distance
52
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
8.355839
seq distance
56
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
8.355839
seq distance
56
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
8.355839
seq distance
56
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
8.355839
seq distance
56
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441045
seq distance
56
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441045
seq distance
56
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441045
seq distance
56
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441045
seq distance
56
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.706487
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.706487
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.706487
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.706487
seq distance
12
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.921886
seq distance
14
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.948237
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.948237
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.948237
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.948237
seq distance
12
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.425432
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.425432
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.425432
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.425432
seq distance
13
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.43578
seq distance
14
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.46922
seq distance
58
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.46922
seq distance
58
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
9.515091
seq distance
58
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
9.515091
seq distance
58
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.532164
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.532164
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.532164
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.532164
seq distance
13
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.716887
seq distance
55
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.716887
seq distance
55
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.772378
seq distance
55
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.772378
seq distance
55
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
10.887521
seq distance
59
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
10.887521
seq distance
59
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.028416
seq distance
59
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.028416
seq distance
59
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.199695
seq distance
17
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.199695
seq distance
17
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.258803
seq distance
23
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.258803
seq distance
23
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.25932
seq distance
22
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.25932
seq distance
22
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.25932
seq distance
22
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.25932
seq distance
22
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.589333
seq distance
23
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.589333
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.6006155
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.6006155
seq distance
18
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.6006155
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.6006155
seq distance
18
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.605853
seq distance
17
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.605853
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.606213
seq distance
18
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.606213
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.606213
seq distance
18
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.606213
seq distance
18
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.877947
seq distance
6
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
12.091383
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
12.091383
seq distance
22
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
12.091383
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
12.091383
seq distance
22
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.4789715
seq distance
6
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.256284
seq distance
65
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.256284
seq distance
65
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
13.34719
seq distance
65
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
13.34719
seq distance
65
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.981615
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.981615
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
14.000779
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
14.000779
seq distance
False
chain
B
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.008224
seq distance
32
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.008224
seq distance
32
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.008224
seq distance
32
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.008224
seq distance
32
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.201492
seq distance
32
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.201492
seq distance
32
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.201492
seq distance
32
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.201492
seq distance
32
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.681791
seq distance
62
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.681791
seq distance
62
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
16.770458
seq distance
62
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
16.770458
seq distance
62
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.86798
seq distance
29
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.86798
seq distance
29
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.01146
seq distance
29
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.01146
seq distance
29
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.221956
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.221956
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.539845
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.539845
seq distance
False
chain
B
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.674267
seq distance
28
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.674267
seq distance
28
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.037111
seq distance
28
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.037111
seq distance
28
chain
C
Details
Redox score
65.65
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
7.59
Half-sphere exposure sum
96
Minimum pKa
nan
% buried
nan
Peptide A name
Vasopressin-neurophysin 2-copeptin
Peptide B name
Vasopressin-neurophysin 2-copeptin
Peptide A accession
P01180
Peptide B accession
P01180
Peptide A residue number
110 (Residue 79 in this structure)
Peptide B residue number
110 (Residue 79 in this structure)
1npo A 79 C 74
A redox-regulated disulphide may form between two units of Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
63.06
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
9.36
Half-sphere exposure sum
97
Minimum pKa
nan
% buried
nan
Peptide A name
Vasopressin-neurophysin 2-copeptin
Peptide B name
Vasopressin-neurophysin 2-copeptin
Peptide A accession
P01180
Peptide B accession
P01180
Peptide A residue number
110 (Residue 79 in this structure)
Peptide B residue number
105 (Residue 74 in this structure)
7kh0 L 1 L 6
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
72.72727272727273
distance
4.7889843
seq distance
1
chain
L
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
72.72727272727273
distance
4.7889843
seq distance
1
chain
L
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
63.63636363636363
distance
6.27496
seq distance
1
chain
L
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
63.63636363636363
distance
6.27496
seq distance
1
chain
L
Gain of antagonist activity on V1aR/AVPR1A (and loss of agonist activity on this receptor). 42-fold decrease in affinity for V1aR/AVPR1A, 2000-fold decrease in affinity for V1bR/AVPR1B, 5-fold decrease in affinity for V2R/AVPR2 and no change in affinity for oxytocin receptor (OXTR).
original residue
G
variation residue
V
position
9
score
54.54545454545454
distance
7.400496
seq distance
3
chain
L
Gain of antagonist activity on V1aR/AVPR1A (and loss of agonist activity on this receptor). 42-fold decrease in affinity for V1aR/AVPR1A, 2000-fold decrease in affinity for V1bR/AVPR1B, 5-fold decrease in affinity for V2R/AVPR2 and no change in affinity for oxytocin receptor (OXTR).
original residue
G
variation residue
V
position
9
score
54.54545454545454
distance
7.400496
seq distance
3
chain
L
Glycine amide
position
9
score
54.54545454545454
distance
7.400496
seq distance
3
chain
L
Glycine amide
position
9
score
54.54545454545454
distance
7.400496
seq distance
3
chain
L
In NDI; probably causes insufficient processing of precursor; dbSNP:rs387906511.
original residue
A
variation residue
T
position
203
score
54.54545454545454
distance
79.13271
seq distance
False
chain
B
In NDI; dbSNP:rs387906512.
original residue
A
variation residue
V
position
203
score
54.54545454545454
distance
79.13271
seq distance
False
chain
B
In NDI; probably causes insufficient processing of precursor; dbSNP:rs387906511.
original residue
A
variation residue
T
position
203
score
54.54545454545454
distance
79.13271
seq distance
False
chain
B
In NDI; dbSNP:rs387906512.
original residue
A
variation residue
V
position
203
score
54.54545454545454
distance
79.13271
seq distance
False
chain
B
In NDI.
original residue
S
variation residue
F
position
201
score
50.0
distance
80.41588
seq distance
False
chain
B
In NDI.
original residue
S
variation residue
F
position
201
score
50.0
distance
80.41588
seq distance
False
chain
B
Details
Redox score
77.51
PDB code
7kh0
Structure name
cryo-em structure of the human arginine vasopressin avp-vasopressin receptor v2r-gs signaling complex
Structure deposition date
2020-10-19
Thiol separation (Å)
2.03
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01185
Residue number A
20 (Residue 1 in this structure)
Residue number B
25 (Residue 6 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 10 C 54
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
4.2275743
seq distance
2
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
4.2275743
seq distance
2
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.973959
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.973959
seq distance
11
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.4466043
seq distance
10
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.4466043
seq distance
10
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
7.5927696
seq distance
13
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
7.5927696
seq distance
13
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
7.5927696
seq distance
13
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
7.5927696
seq distance
13
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.7839913
seq distance
7
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.7839913
seq distance
7
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.7839913
seq distance
7
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.7839913
seq distance
7
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
7.926058
seq distance
3
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
7.926058
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
7.926058
seq distance
3
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
7.926058
seq distance
3
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.294953
seq distance
4
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.294953
seq distance
4
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
9.503683
seq distance
14
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
9.503683
seq distance
14
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.790944
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.790944
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.790944
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.790944
seq distance
12
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.976667
seq distance
14
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.976667
seq distance
14
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
10.009661
seq distance
3
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
10.009661
seq distance
3
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
10.030966
seq distance
17
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
10.030966
seq distance
17
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
10.345958
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
10.345958
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
10.345958
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
10.345958
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
11.554022
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
11.554022
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
11.554022
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
11.554022
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.670729
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.670729
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.670729
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.670729
seq distance
20
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.707546
seq distance
11
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.099879
seq distance
7
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.099879
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.802057
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.802057
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.802057
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.802057
seq distance
19
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.8783655
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.8783655
seq distance
4
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
14.69878
seq distance
7
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
14.69878
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
14.69878
seq distance
7
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
14.69878
seq distance
7
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.468267
seq distance
18
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.468267
seq distance
18
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.738886
seq distance
8
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.738886
seq distance
8
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
16.789854
seq distance
31
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
18.511818
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
18.511818
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
23.103416
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
23.103416
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
23.103416
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
23.103416
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
23.405779
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
23.405779
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
23.405779
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
23.405779
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
24.350332
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
24.350332
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
24.350332
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
24.350332
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
24.376131
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
24.376131
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
25.831743
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
25.968782
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
25.968782
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
26.482918
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
26.482918
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
26.703127
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
26.703127
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
26.703127
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
26.703127
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
26.734709
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
26.734709
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
26.792656
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
26.792656
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
26.792656
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
26.792656
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
27.125286
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
27.125286
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
27.15693
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
28.07239
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
28.07239
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
28.07239
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
28.07239
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
28.149006
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
28.149006
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
28.149006
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
28.149006
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
28.374022
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
28.374022
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
29.403296
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
29.403296
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
31.529192
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
31.529192
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.317364
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.317364
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.317364
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.317364
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
33.64512
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
33.64512
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
35.45458
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
35.45458
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
35.45458
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
35.45458
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
37.156208
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
37.156208
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
37.92297
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
37.92297
seq distance
False
chain
A
Details
Redox score
77.13
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
2.02
Half-sphere exposure sum
53
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
41 (Residue 10 in this structure)
Residue number B
85 (Residue 54 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 67 C 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
2.8106098
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.8140984
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.8140984
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.8140984
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.8140984
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.9830494
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.9830494
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.9830494
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.9830494
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.2281866
seq distance
6
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.2281866
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.2281866
seq distance
6
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.2281866
seq distance
6
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.4028435
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.4028435
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.4028435
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.4028435
seq distance
1
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.5297565
seq distance
1
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.5297565
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
7.4744596
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
7.4744596
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
7.4744596
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
7.4744596
seq distance
7
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.691144
seq distance
5
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.691144
seq distance
5
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.868946
seq distance
2
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.490357
seq distance
10
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.490357
seq distance
10
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.490357
seq distance
10
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.490357
seq distance
10
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.469245
seq distance
11
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.469245
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.699478
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.699478
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.699478
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.699478
seq distance
39
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.857686
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.857686
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.382228
seq distance
47
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.382228
seq distance
47
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.4920435
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.4920435
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
15.152739
seq distance
46
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
15.152739
seq distance
46
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.489966
seq distance
44
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.489966
seq distance
44
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.489966
seq distance
44
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.489966
seq distance
44
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.925226
seq distance
31
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.925226
seq distance
31
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.022932
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.022932
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.626032
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.626032
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.626032
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.626032
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
17.724058
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
17.724058
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
17.724058
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
17.724058
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
19.037287
seq distance
43
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
19.037287
seq distance
43
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.142614
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.142614
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.305214
seq distance
53
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.305214
seq distance
53
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
19.954395
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
19.954395
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
19.954395
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
19.954395
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.351019
seq distance
50
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.351019
seq distance
50
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
20.780994
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.966768
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.966768
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.966768
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.966768
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.06222
seq distance
20
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.06222
seq distance
20
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.06222
seq distance
20
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.06222
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.455032
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.455032
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.069298
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.069298
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.069298
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.069298
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.091753
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.091753
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
22.341013
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
22.341013
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
22.979273
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
22.979273
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
22.979273
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
22.979273
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.609627
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.609627
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.675201
seq distance
16
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.675201
seq distance
16
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
23.715147
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
23.715147
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
23.715147
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
23.715147
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.940054
seq distance
17
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.940054
seq distance
17
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.200626
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.200626
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.310503
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.310503
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.310503
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.310503
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
25.934937
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.090229
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.090229
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.266043
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.266043
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.801672
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.801672
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.269512
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.269512
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
30.550154
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
30.550154
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
30.550154
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
30.550154
seq distance
False
chain
A
Details
Redox score
76.12
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
2.03
Half-sphere exposure sum
61
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
98 (Residue 67 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 61 C 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.7916176
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.7916176
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.7916176
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.7916176
seq distance
0
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.8262
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.4415479
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.4415479
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.4415479
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.4415479
seq distance
6
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.7232995
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.7232995
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.7232995
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.7232995
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.7800007
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.7800007
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.7800007
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.7800007
seq distance
12
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.6187816
seq distance
4
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.259917
seq distance
1
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.259917
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.033328
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.033328
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.033328
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.033328
seq distance
11
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.522625
seq distance
7
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.522625
seq distance
7
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.261062
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.261062
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.261062
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.261062
seq distance
4
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.65602
seq distance
5
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.65602
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.6821995
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.6821995
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.6821995
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.6821995
seq distance
33
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.298975
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.298975
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
13.54524
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
13.54524
seq distance
38
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
13.54524
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
13.54524
seq distance
38
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
14.177821
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
14.177821
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.303685
seq distance
34
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.303685
seq distance
34
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
14.339719
seq distance
41
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
14.339719
seq distance
41
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.428251
seq distance
25
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.428251
seq distance
25
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
15.814559
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
15.814559
seq distance
False
chain
D
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.901611
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.901611
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
17.138094
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
17.138094
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
17.138094
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
17.138094
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.186897
seq distance
37
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.186897
seq distance
37
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.709778
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.709778
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.709778
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.709778
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.685144
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.685144
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.685144
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.685144
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.277369
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.277369
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
19.432526
seq distance
47
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
19.432526
seq distance
47
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.945177
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.945177
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.454294
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.454294
seq distance
14
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.454294
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.454294
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
20.556795
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
20.846634
seq distance
44
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
20.846634
seq distance
44
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.881403
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.881403
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.881403
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.881403
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.484858
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.484858
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
22.063383
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
22.063383
seq distance
False
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.514853
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.514853
seq distance
False
chain
B
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
22.536661
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
22.536661
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
22.536661
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
22.536661
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
22.558247
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
22.558247
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
22.558247
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
22.558247
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.902987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.902987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.902987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.902987
seq distance
False
chain
A
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.9713
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.9713
seq distance
False
chain
D
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.70856
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.70856
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.870432
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.870432
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.870432
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.870432
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.948524
seq distance
11
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.948524
seq distance
11
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.445349
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.445349
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
24.731113
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.810453
seq distance
10
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.810453
seq distance
10
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.342207
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.342207
seq distance
False
chain
A
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
26.684177
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
26.684177
seq distance
False
chain
B
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
26.808157
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
26.808157
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
26.808157
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
26.808157
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.163637
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.163637
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.45492
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.45492
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.64365
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.64365
seq distance
False
chain
A
Details
Redox score
75.98
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.15
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
92 (Residue 61 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 21 C 44
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.8223956
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.8223956
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.3154097
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.3154097
seq distance
6
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.146359
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.146359
seq distance
1
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.698347
seq distance
3
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.698347
seq distance
3
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.124095
seq distance
2
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.124095
seq distance
2
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.124095
seq distance
2
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.124095
seq distance
2
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.8374395
seq distance
3
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.8374395
seq distance
3
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.8374395
seq distance
3
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.8374395
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.6203413
seq distance
7
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.6203413
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.825041
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.825041
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.825041
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.825041
seq distance
7
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.778084
seq distance
8
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.778084
seq distance
8
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.25413
seq distance
4
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.25413
seq distance
4
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.085226
seq distance
12
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.085226
seq distance
12
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
11.359361
seq distance
6
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
11.359361
seq distance
6
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.6065235
seq distance
24
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.6065235
seq distance
24
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.44804
seq distance
30
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.44804
seq distance
30
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.44804
seq distance
30
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.44804
seq distance
30
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
13.917758
seq distance
7
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
13.917758
seq distance
7
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.184614
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.184614
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.270657
seq distance
22
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.270657
seq distance
22
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.270657
seq distance
22
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.270657
seq distance
22
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
14.767214
seq distance
13
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
14.767214
seq distance
13
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
14.767214
seq distance
13
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
14.767214
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.097781
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.097781
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.097781
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.097781
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.374565
seq distance
29
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.374565
seq distance
29
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.374565
seq distance
29
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.374565
seq distance
29
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.615584
seq distance
21
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.360712
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.360712
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.360712
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.360712
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.28783
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.28783
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.344162
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.344162
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.344162
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.344162
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.933851
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.933851
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.933851
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.933851
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.260191
seq distance
17
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.260191
seq distance
17
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.260191
seq distance
17
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.260191
seq distance
17
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.50781
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.50781
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.581526
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.581526
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
19.82129
seq distance
41
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.119358
seq distance
18
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.119358
seq distance
18
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
20.247786
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.914394
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.914394
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.914394
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.914394
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
22.642166
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
22.642166
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
22.653156
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
22.653156
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.69752
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.69752
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.69752
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.69752
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.092283
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.092283
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.092283
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.092283
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.292364
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
23.545307
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
23.545307
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
23.709324
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
23.709324
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.908628
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.908628
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.074741
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.074741
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.074741
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.074741
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.229637
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.229637
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.224274
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.224274
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.224274
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.224274
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
28.788706
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
28.788706
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
28.788706
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
28.788706
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.256054
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.256054
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
34.51193
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
34.51193
seq distance
False
chain
A
Details
Redox score
75.73
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
2.03
Half-sphere exposure sum
76
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
52 (Residue 21 in this structure)
Residue number B
75 (Residue 44 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 61 C 73
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.8159366
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.8159366
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.8159366
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.8159366
seq distance
0
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.033884
seq distance
1
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.033884
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.6890526
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.6890526
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.6890526
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.6890526
seq distance
1
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.63216
seq distance
12
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.9176965
seq distance
5
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.9176965
seq distance
5
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.708506
seq distance
5
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.708506
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.257134
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.257134
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.257134
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.257134
seq distance
33
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
13.069653
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
13.069653
seq distance
38
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
13.069653
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
13.069653
seq distance
38
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.1834345
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.1834345
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.138124
seq distance
34
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.138124
seq distance
34
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
14.170941
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
14.170941
seq distance
40
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.473505
seq distance
41
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.473505
seq distance
41
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.588487
seq distance
25
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.588487
seq distance
25
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.399379
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.399379
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.399379
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.399379
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.61555
seq distance
37
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.61555
seq distance
37
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.054625
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.054625
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.054625
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.054625
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.512003
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.512003
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.512003
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.512003
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.93158
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.93158
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.067072
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.444508
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.444508
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
18.992632
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
18.992632
seq distance
14
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
18.992632
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
18.992632
seq distance
14
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.119541
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.119541
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.867125
seq distance
47
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.867125
seq distance
47
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.206852
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.206852
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
20.206852
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
20.206852
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
20.463728
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
20.463728
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.521473
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.521473
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.521473
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.521473
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.986849
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.986849
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.986849
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.986849
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.152424
seq distance
10
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.152424
seq distance
10
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.153692
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.153692
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.153692
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.153692
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.24261
seq distance
44
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.24261
seq distance
44
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.397343
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.397343
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.79747
seq distance
11
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.79747
seq distance
11
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
22.768589
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.935795
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.935795
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.935795
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.935795
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
23.927273
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
23.927273
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
24.279106
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
24.279106
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
26.50104
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
26.50104
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.599667
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.599667
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.835907
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.835907
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.706234
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.706234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
28.81115
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
28.81115
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
28.81115
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
28.81115
seq distance
False
chain
A
Details
Redox score
75.53
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
2.04
Half-sphere exposure sum
65
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
92 (Residue 61 in this structure)
Residue number B
104 (Residue 73 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk4 A 28 A 34
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8468738
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8468738
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8468738
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8468738
seq distance
0
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.5696936
seq distance
34
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.5696936
seq distance
34
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.6508217
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.6508217
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.028596
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.028596
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.028596
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.028596
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.715884
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.715884
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.715884
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.715884
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.031809
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.031809
seq distance
7
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.151466
seq distance
2
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.151466
seq distance
2
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.4553146
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.4553146
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.9009542
seq distance
33
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.9009542
seq distance
33
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.9009542
seq distance
33
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.9009542
seq distance
33
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441477
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441477
seq distance
5
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441477
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441477
seq distance
5
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.921921
seq distance
23
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.921921
seq distance
23
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.921921
seq distance
23
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.921921
seq distance
23
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.088061
seq distance
32
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.088061
seq distance
32
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.088061
seq distance
32
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.088061
seq distance
32
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.224468
seq distance
22
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.224468
seq distance
22
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.156858
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.156858
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.329629
seq distance
31
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
10.638767
seq distance
51
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.0880995
seq distance
4
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.0880995
seq distance
4
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.676747
seq distance
27
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.676747
seq distance
27
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.676747
seq distance
27
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.676747
seq distance
27
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.017597
seq distance
11
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.017597
seq distance
11
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.448446
seq distance
28
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.448446
seq distance
28
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
54.54545454545454
distance
13.646359
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
54.54545454545454
distance
13.646359
seq distance
False
chain
B
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.958871
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.958871
seq distance
13
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.958871
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.958871
seq distance
13
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.706848
seq distance
16
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.706848
seq distance
16
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.828205
seq distance
17
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.828205
seq distance
17
chain
A
Details
Redox score
75.04
PDB code
1jk4
Structure name
des 1-6 bovine neurophysin ii complex with vasopressin
Structure deposition date
2001-07-11
Thiol separation (Å)
2.04
Half-sphere exposure sum
84
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
65 (Residue 34 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 G 13 G 27
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7876592
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7876592
seq distance
0
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.522127
seq distance
7
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.522127
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.087475
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.087475
seq distance
6
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.272046
seq distance
1
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.272046
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.7899294
seq distance
4
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.7899294
seq distance
4
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.390303
seq distance
9
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.390303
seq distance
9
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.819275
seq distance
4
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.819275
seq distance
4
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.819275
seq distance
4
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.819275
seq distance
4
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.474928
seq distance
3
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.474928
seq distance
3
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.511335
seq distance
29
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.511335
seq distance
29
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
9.887008
seq distance
41
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
9.887008
seq distance
41
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
10.827437
seq distance
20
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
10.827437
seq distance
20
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
10.827437
seq distance
20
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
10.827437
seq distance
20
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.034115
seq distance
30
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.034115
seq distance
30
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.034115
seq distance
30
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.034115
seq distance
30
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
11.582963
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
11.582963
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.07094
seq distance
47
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.07094
seq distance
47
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.07094
seq distance
47
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.07094
seq distance
47
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.649834
seq distance
40
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.649834
seq distance
40
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.649834
seq distance
40
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.649834
seq distance
40
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.96276
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.96276
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.96276
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.96276
seq distance
46
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.399562
seq distance
39
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.399562
seq distance
39
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.399562
seq distance
39
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.399562
seq distance
39
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
15.491522
seq distance
23
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
15.491522
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
15.976604
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
15.976604
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
15.976604
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
15.976604
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
16.101225
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
16.101225
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
16.239073
seq distance
38
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.08812
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.08812
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.676573
seq distance
58
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
18.489937
seq distance
24
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
18.489937
seq distance
24
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.706516
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.706516
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.706516
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.706516
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.711323
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.711323
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.763367
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.763367
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
18.763367
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
18.763367
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.769943
seq distance
34
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.769943
seq distance
34
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.769943
seq distance
34
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.769943
seq distance
34
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.21109
seq distance
35
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.21109
seq distance
35
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
20.602665
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
20.602665
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
20.643875
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
20.643875
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
20.643875
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
20.643875
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
20.721546
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
20.721546
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
21.03523
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
21.03523
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.131266
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.131266
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.131266
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.131266
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
21.548843
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.96587
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.96587
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.215467
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.215467
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.215467
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.215467
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.439167
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
24.13778
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
24.13778
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.159828
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.159828
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.159828
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.159828
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
24.599735
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
24.599735
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.726267
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.726267
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
24.726267
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
24.726267
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.764927
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.764927
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.764927
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.764927
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.76205
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.76205
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
32.108036
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
32.108036
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
32.117878
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
32.117878
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
35.03737
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
35.03737
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
35.238277
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
35.238277
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
35.420704
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
35.420704
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
35.420704
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
35.420704
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.366985
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.366985
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
36.591454
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
36.591454
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
38.126553
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
38.126553
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
39.987286
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
39.987286
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
41.781837
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
41.781837
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
41.784138
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
41.784138
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
41.784138
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
41.784138
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
42.083355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
42.083355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
42.083355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
42.083355
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
42.0884
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
42.0884
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.84799
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.84799
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.84142
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.84142
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.84142
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.84142
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
48.311916
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
48.311916
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.911
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.911
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
51.081093
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
51.081093
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
56.3038
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
56.3038
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
56.42479
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
56.42479
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
56.454445
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
56.454445
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
56.454445
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
56.454445
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
57.397217
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
57.397217
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
57.397217
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
57.397217
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
57.792953
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
57.792953
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
57.792953
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
57.792953
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
58.64154
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
58.64154
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
59.247536
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.39302
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.39302
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.94663
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.94663
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.94663
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.94663
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
60.57291
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
60.57291
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
60.57291
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
60.57291
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
60.771446
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
60.771446
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
60.904785
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
60.904785
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
61.296154
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
61.296154
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
61.45627
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
61.45627
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
62.51181
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
62.53022
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
62.53022
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
62.53022
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
62.53022
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
62.828953
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
62.828953
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
62.828953
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
62.828953
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
64.5965
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
64.5965
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
64.5965
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
64.5965
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
65.21719
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
65.21719
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.571
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.571
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.571
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.571
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.85646
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.85646
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.793236
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.793236
seq distance
False
chain
C
Details
Redox score
74.35
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
2.03
Half-sphere exposure sum
88
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
44 (Residue 13 in this structure)
Residue number B
58 (Residue 27 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 13 A 44
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.5729246
seq distance
14
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.5729246
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.9780936
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.9780936
seq distance
7
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.8381853
seq distance
1
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.8381853
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
5.782493
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
5.782493
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
5.782493
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
5.782493
seq distance
15
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
11
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
11
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
10
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
10
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
10
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
10
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.806053
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.806053
seq distance
4
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.551682
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.551682
seq distance
8
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.879648
seq distance
12
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.879648
seq distance
12
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.331644
seq distance
24
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.331644
seq distance
24
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
10.658963
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
10.658963
seq distance
False
chain
B
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.715612
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.715612
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.715612
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.715612
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.880601
seq distance
6
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.880601
seq distance
6
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.314392
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.314392
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.900677
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.900677
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.900677
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.900677
seq distance
23
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.547252
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.547252
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.547252
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.547252
seq distance
22
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.614567
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.614567
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.614567
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.614567
seq distance
29
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.889215
seq distance
7
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.889215
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
17.854465
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
17.854465
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.475536
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.475536
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.475536
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.475536
seq distance
17
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.495405
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
18.81649
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
18.81649
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
18.834488
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
18.834488
seq distance
False
chain
B
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.779902
seq distance
18
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.779902
seq distance
18
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
22.251589
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
22.251589
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
22.28957
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
22.28957
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
22.28957
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
22.28957
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
22.34849
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
22.34849
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
22.36187
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
22.36187
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
23.57846
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
23.57846
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.447021
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.447021
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.284042
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.284042
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.284042
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.284042
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
28.723175
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
28.723175
seq distance
False
chain
D
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.56542
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.56542
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.500328
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.500328
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
36.589893
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
36.589893
seq distance
False
chain
D
Details
Redox score
74.21
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.39
Half-sphere exposure sum
73
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
44 (Residue 13 in this structure)
Residue number B
75 (Residue 44 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 61 A 67
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
No relevant regions found.
Details
Redox score
73.81
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.15
Half-sphere exposure sum
62
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
92 (Residue 61 in this structure)
Residue number B
98 (Residue 67 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 13 A 21
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
No relevant regions found.
Details
Redox score
72.96
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.37
Half-sphere exposure sum
83
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
44 (Residue 13 in this structure)
Residue number B
52 (Residue 21 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 28 C 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
No relevant regions found.
Details
Redox score
72.84
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.32
Half-sphere exposure sum
101
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 34 C 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
No relevant regions found.
Details
Redox score
72.34
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
3.2
Half-sphere exposure sum
102
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
65 (Residue 34 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 E 73 E 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.821786
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.5363588
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.5363588
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.5363588
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.5363588
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.0306683
seq distance
11
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.0306683
seq distance
11
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.5333962
seq distance
5
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.5333962
seq distance
5
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.543932
seq distance
16
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.543932
seq distance
16
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.543932
seq distance
16
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.543932
seq distance
16
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.791437
seq distance
45
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.791437
seq distance
45
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.791437
seq distance
45
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.791437
seq distance
45
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.841757
seq distance
17
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.841757
seq distance
17
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.758488
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.758488
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
12.898715
seq distance
50
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
12.898715
seq distance
50
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
12.898715
seq distance
50
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
12.898715
seq distance
50
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.027727
seq distance
46
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.027727
seq distance
46
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.256204
seq distance
37
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.256204
seq distance
37
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
14.366251
seq distance
52
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
14.366251
seq distance
52
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.986418
seq distance
53
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.986418
seq distance
53
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.200265
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.200265
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.200265
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.200265
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.40933
seq distance
49
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.40933
seq distance
49
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.47111
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.47111
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
16.557026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
16.557026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
16.557026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
16.557026
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.205418
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.205418
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
17.205418
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
17.205418
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.092606
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.092606
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.700954
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.700954
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.723392
seq distance
59
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.723392
seq distance
59
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.799473
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.799473
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.8026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.8026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.8026
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.8026
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.471792
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.471792
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.471792
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.471792
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.482422
seq distance
26
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.482422
seq distance
26
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.482422
seq distance
26
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.482422
seq distance
26
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.747952
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.747952
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.747952
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.747952
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.77126
seq distance
56
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.77126
seq distance
56
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.113127
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
21.113127
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.560822
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.450981
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.450981
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.450981
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.450981
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
23.534422
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
23.534422
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.587782
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
23.587782
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
23.866526
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
23.866526
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.983843
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.983843
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.983843
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.983843
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.101828
seq distance
23
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.101828
seq distance
23
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.045956
seq distance
22
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.045956
seq distance
22
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
26.416178
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
26.416178
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.908484
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.908484
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.11968
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
28.11968
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.454111
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.454111
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.863245
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.863245
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
30.130745
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
30.130745
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
30.130745
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
30.130745
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.261457
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.261457
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
30.688265
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
30.688265
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
31.634993
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
31.634993
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
33.292416
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
33.292416
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
35.106567
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
35.106567
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
35.27185
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
35.27185
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
36.07608
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
36.07608
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
36.2281
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
36.2281
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
36.2281
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
36.2281
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
36.9396
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
36.9396
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
36.9396
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
36.9396
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
37.33928
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
37.33928
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
37.33928
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
37.33928
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
39.518063
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
39.518063
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.033356
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.033356
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
41.91181
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
41.91181
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
41.91181
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
41.91181
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.05879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.05879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.05879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.05879
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
42.928577
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
42.928577
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
42.928577
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
42.928577
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
44.0667
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
44.0667
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.28631
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
44.658066
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
44.658066
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
44.658066
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
44.658066
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
45.19143
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
45.19143
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
45.34794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.241123
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.241123
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.241123
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.241123
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
47.454636
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
47.454636
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
47.454636
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
47.454636
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
47.566483
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
47.566483
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
49.077164
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
49.077164
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.398453
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.398453
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
50.37007
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
50.37007
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
50.814922
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
50.814922
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
50.814922
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
50.814922
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
51.35349
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
51.474415
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
51.474415
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
51.474415
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
51.474415
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
51.66491
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
51.66491
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
51.875973
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
51.875973
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
52.263332
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
52.263332
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
52.77556
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
52.77556
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
52.77556
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
52.77556
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
52.93982
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
52.93982
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
52.93982
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
52.93982
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
55.711857
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
55.711857
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
55.711857
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
55.711857
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
55.978775
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
55.978775
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
55.978775
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
55.978775
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
56.12991
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
56.12991
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
56.50833
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
56.50833
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
56.50833
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
56.50833
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
56.625523
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
56.768875
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
56.768875
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
56.992825
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
56.992825
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
56.992825
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
56.992825
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
62.048347
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
62.048347
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
65.49322
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
65.49322
seq distance
False
chain
C
Details
Redox score
71.25
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
5.01
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
104 (Residue 73 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 A 34 A 79
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.1172643
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.1172643
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.1172643
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.1172643
seq distance
5
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
5.073697
seq distance
11
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
5.073697
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1930623
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1930623
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.2126374
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.2126374
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.2126374
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.2126374
seq distance
6
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.2931514
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.2931514
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.447158
seq distance
2
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.447158
seq distance
2
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.89974
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.89974
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.89974
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.89974
seq distance
12
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.472672
seq distance
11
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.472672
seq distance
11
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.472672
seq distance
11
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.472672
seq distance
11
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.888387
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
8.943929
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
8.943929
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
8.943929
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
8.943929
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.119647
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.119647
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.177613
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.177613
seq distance
14
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
10.873
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.016838
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.016838
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.016838
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.016838
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.060635
seq distance
10
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.060635
seq distance
10
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.136065
seq distance
20
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.136065
seq distance
20
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.844182
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.844182
seq distance
18
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.844182
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.844182
seq distance
18
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.916474
seq distance
17
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.916474
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.133029
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.133029
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.133029
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.133029
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
12.356309
seq distance
22
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
12.356309
seq distance
22
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.726713
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.726713
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.21211
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.21211
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.21211
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.21211
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.030176
seq distance
17
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.030176
seq distance
17
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.212649
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.212649
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.212649
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.212649
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
14.323886
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
14.323886
seq distance
22
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
14.323886
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
14.323886
seq distance
22
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.34788
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.34788
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.767627
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.767627
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.022096
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.022096
seq distance
13
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.022096
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.022096
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.597404
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.826559
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.826559
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.826559
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.826559
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.124249
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.124249
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.198315
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.198315
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.258179
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.258179
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.30174
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.30174
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.30174
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.30174
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.16843
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.694632
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.694632
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.694632
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.694632
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.802717
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.802717
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.335892
seq distance
16
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.335892
seq distance
16
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.884724
seq distance
17
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.884724
seq distance
17
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.038082
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.038082
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.534895
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.534895
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.565891
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.565891
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.565891
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.565891
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.919987
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.919987
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.584757
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.584757
seq distance
False
chain
C
Details
Redox score
71.05
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
3.87
Half-sphere exposure sum
101
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
65 (Residue 34 in this structure)
Residue number B
110 (Residue 79 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 28 C 79
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.9086199
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.9086199
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.9086199
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.9086199
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.600761
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.600761
seq distance
1
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6844206
seq distance
11
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6844206
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.2950625
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.2950625
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.2950625
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.2950625
seq distance
6
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4113054
seq distance
8
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4113054
seq distance
8
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.170532
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.170532
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.1850986
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.1850986
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.3390365
seq distance
8
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.3390365
seq distance
8
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.098035
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.098035
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.098035
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.098035
seq distance
12
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.503073
seq distance
5
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.503073
seq distance
5
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.503073
seq distance
5
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.503073
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
8.934707
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
8.934707
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
8.934707
seq distance
13
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
8.934707
seq distance
13
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.1596775
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.09827
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.09827
seq distance
14
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.994541
seq distance
4
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.994541
seq distance
4
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.061462
seq distance
23
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.061462
seq distance
23
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.586144
seq distance
17
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.586144
seq distance
17
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.811459
seq distance
18
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.811459
seq distance
18
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.811459
seq distance
18
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.811459
seq distance
18
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
11.831222
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.796858
seq distance
11
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.796858
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.8436775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.8436775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
13.301628
seq distance
22
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
13.301628
seq distance
22
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
13.301628
seq distance
22
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
13.301628
seq distance
22
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.02133
seq distance
19
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.02133
seq distance
19
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.02133
seq distance
19
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.02133
seq distance
19
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.271904
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.271904
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.117569
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.117569
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.17937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.17937
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.328785
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.328785
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.136438
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.136438
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.778835
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.778835
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
18.491879
seq distance
22
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
18.491879
seq distance
22
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.635172
seq distance
23
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.635172
seq distance
23
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.31582
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.31582
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.835161
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.835161
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.808535
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.808535
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.386211
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.386211
seq distance
False
chain
A
Details
Redox score
70.96
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
4.41
Half-sphere exposure sum
96
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
110 (Residue 79 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 27 A 44
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7588584
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7588584
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
6
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
3.7661886
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
3.7661886
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.7907357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.7907357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.7907357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.7907357
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.1452527
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.1452527
seq distance
7
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
3
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
3
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
4
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
4
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
4
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.0811453
seq distance
10
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.0811453
seq distance
10
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.630088
seq distance
3
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.444317
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.444317
seq distance
8
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.027406
seq distance
24
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.027406
seq distance
24
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.486069
seq distance
12
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.486069
seq distance
12
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
10.658963
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
10.658963
seq distance
False
chain
B
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
11.656036
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
11.656036
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.00678
seq distance
30
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
12.404935
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
12.404935
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
12.404935
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
12.404935
seq distance
13
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.880601
seq distance
6
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.880601
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.753501
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.753501
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.753501
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.753501
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.133636
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.133636
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.133636
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.133636
seq distance
29
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
14.704222
seq distance
21
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.810982
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.810982
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
14.810982
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
14.810982
seq distance
22
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.889215
seq distance
7
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.889215
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
15.92472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
15.92472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
15.92472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
15.92472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
16.020191
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
16.020191
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
16.845861
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
16.845861
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.962173
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.509226
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.509226
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.509226
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.509226
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.532671
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.532671
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.532671
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.532671
seq distance
17
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
18.834488
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
18.834488
seq distance
False
chain
B
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.779902
seq distance
18
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.779902
seq distance
18
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
20.439663
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
20.439663
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
20.623415
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
20.623415
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
20.639221
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
20.639221
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
20.639221
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
20.639221
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
20.820877
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
20.820877
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.670567
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.670567
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.492865
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.492865
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.492865
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.492865
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
24.641687
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
24.641687
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.39882
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.39882
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.39882
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.39882
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
27.101734
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
27.101734
seq distance
False
chain
D
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
31.676163
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
31.676163
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
34.6681
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
34.6681
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
35.02574
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
35.02574
seq distance
False
chain
D
Details
Redox score
70.69
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
4.45
Half-sphere exposure sum
91
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
58 (Residue 27 in this structure)
Residue number B
75 (Residue 44 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 67 A 73
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.7708235
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.7708235
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.7708235
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.7708235
seq distance
0
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
3.485363
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.5846667
seq distance
6
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.5846667
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.5846667
seq distance
6
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.5846667
seq distance
6
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.2514434
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.2514434
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.2514434
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.2514434
seq distance
1
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.348892
seq distance
5
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.348892
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.764726
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.764726
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.764726
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.764726
seq distance
1
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.160844
seq distance
2
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.3839693
seq distance
1
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.3839693
seq distance
1
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.275777
seq distance
10
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.275777
seq distance
10
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.275777
seq distance
10
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.275777
seq distance
10
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.927702
seq distance
11
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.927702
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.829946
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.829946
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
11.829946
seq distance
39
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
11.829946
seq distance
39
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
12.697149
seq distance
44
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
12.697149
seq distance
44
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
12.697149
seq distance
44
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
12.697149
seq distance
44
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.820261
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
12.820261
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.848765
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.848765
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
13.855291
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
13.855291
seq distance
46
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.041368
seq distance
47
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
14.041368
seq distance
47
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.323128
seq distance
31
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
14.323128
seq distance
31
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
15.369375
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
15.369375
seq distance
False
chain
B
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.536609
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.536609
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
15.536609
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
15.536609
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.221554
seq distance
43
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.221554
seq distance
43
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
16.888172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
16.888172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
16.888172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
16.888172
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.37408
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.37408
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
17.4513
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
17.4513
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
17.4513
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
17.4513
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.590923
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
17.590923
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.317692
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.950254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.950254
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.374136
seq distance
53
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
19.374136
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.846796
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.846796
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.846796
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.846796
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.914362
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
19.914362
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.920658
seq distance
20
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.920658
seq distance
20
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.920658
seq distance
20
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.920658
seq distance
20
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.339685
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.339685
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.339685
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.339685
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.350634
seq distance
50
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
20.350634
seq distance
50
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.917145
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.917145
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.917145
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.917145
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.032894
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.032894
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
21.032894
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
21.032894
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
21.256744
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
21.256744
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.280592
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.280592
seq distance
False
chain
D
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.399828
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
23.364506
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
23.364506
seq distance
False
chain
B
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.668242
seq distance
17
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.668242
seq distance
17
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
23.744728
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
23.744728
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
23.840876
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
23.840876
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
23.945494
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
23.945494
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.267202
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.267202
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.267202
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.267202
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.418219
seq distance
16
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.418219
seq distance
16
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
24.77701
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
24.77701
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
24.77701
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
24.77701
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.312391
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.312391
seq distance
False
chain
D
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
28.574785
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
28.574785
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.306492
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.306492
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.985537
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.985537
seq distance
False
chain
C
Details
Redox score
68.87
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
4.96
Half-sphere exposure sum
79
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
98 (Residue 67 in this structure)
Residue number B
104 (Residue 73 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk4 A 10 A 21
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.8027012
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.8027012
seq distance
0
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
4.94312
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
4.94312
seq distance
1
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
5.012095
seq distance
35
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
5.012095
seq distance
35
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
54.54545454545454
distance
5.1027966
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
54.54545454545454
distance
5.1027966
seq distance
False
chain
B
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
5.2883267
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
5.2883267
seq distance
6
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.749585
seq distance
2
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.749585
seq distance
2
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.749585
seq distance
2
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.749585
seq distance
2
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.8512344
seq distance
3
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.8512344
seq distance
3
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.852419
seq distance
26
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.852419
seq distance
26
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.852419
seq distance
26
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.852419
seq distance
26
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
8.090735
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
8.090735
seq distance
4
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
8.145198
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
8.145198
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
8.145198
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
8.145198
seq distance
7
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.743737
seq distance
36
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.743737
seq distance
36
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.743737
seq distance
36
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.743737
seq distance
36
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.195774
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.195774
seq distance
4
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.86634
seq distance
29
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.86634
seq distance
29
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.586587
seq distance
15
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.586587
seq distance
15
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
10.83508
seq distance
45
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
10.83508
seq distance
45
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
10.83508
seq distance
45
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
10.83508
seq distance
45
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.291199
seq distance
30
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.291199
seq distance
30
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.40317
seq distance
47
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.40317
seq distance
47
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.467394
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.467394
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.467394
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.467394
seq distance
53
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.762647
seq distance
44
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.024908
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.024908
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.024908
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.024908
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.27629
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.27629
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.27629
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.27629
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.000555
seq distance
40
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.000555
seq distance
40
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.000555
seq distance
40
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.000555
seq distance
40
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.221504
seq distance
41
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.221504
seq distance
41
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.409256
seq distance
64
chain
A
Details
Redox score
67.64
PDB code
1jk4
Structure name
des 1-6 bovine neurophysin ii complex with vasopressin
Structure deposition date
2001-07-11
Thiol separation (Å)
6.74
Half-sphere exposure sum
84
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
41 (Residue 10 in this structure)
Residue number B
52 (Residue 21 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 21 C 27
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
67.45
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
5.47
Half-sphere exposure sum
104
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
52 (Residue 21 in this structure)
Residue number B
58 (Residue 27 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 A 74 A 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.842664
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.842664
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.842664
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.842664
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.3135967
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.3135967
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.3135967
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.3135967
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.237311
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.237311
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.237311
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.237311
seq distance
1
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.942938
seq distance
6
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.942938
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.1655383
seq distance
13
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.1655383
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.1655383
seq distance
13
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.1655383
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.7542157
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.7542157
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.7542157
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.7542157
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.2750297
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.2750297
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.2750297
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.2750297
seq distance
46
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.306356
seq distance
12
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.306356
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.627836
seq distance
47
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.627836
seq distance
47
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.646759
seq distance
9
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.796211
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.796211
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.8995323
seq distance
38
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.8995323
seq distance
38
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.550336
seq distance
51
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.550336
seq distance
51
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.550336
seq distance
51
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.550336
seq distance
51
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.182537
seq distance
17
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.182537
seq distance
17
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.182537
seq distance
17
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.182537
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.322885
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.322885
seq distance
53
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.16737
seq distance
18
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.16737
seq distance
18
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.293586
seq distance
54
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.293586
seq distance
54
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.568246
seq distance
50
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.568246
seq distance
50
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.783073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.783073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.783073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.783073
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.536219
seq distance
60
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.536219
seq distance
60
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.939172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.939172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.939172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.939172
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.00733
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.00733
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.51185
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.51185
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.51185
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.51185
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.8625555
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.8625555
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.8625555
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.8625555
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.475451
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.475451
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.74491
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.74491
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.254248
seq distance
27
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.254248
seq distance
27
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.254248
seq distance
27
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.254248
seq distance
27
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.256897
seq distance
57
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.256897
seq distance
57
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.301159
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.382872
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.382872
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.400738
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.400738
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.614883
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.614883
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.614883
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.614883
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.371294
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.371294
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.42006
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.42006
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.42006
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.42006
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.005163
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.146242
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.146242
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.146242
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.146242
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.223549
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.223549
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.80846
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.80846
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.856771
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.856771
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.856771
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.856771
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.866093
seq distance
24
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.866093
seq distance
24
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.409925
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.409925
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.409925
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.409925
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.866268
seq distance
23
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.866268
seq distance
23
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.650171
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.650171
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.689066
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.689066
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.661236
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.661236
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.017313
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.017313
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
25.95702
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
25.95702
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
25.95702
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
25.95702
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.629032
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.629032
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
28.141136
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
28.141136
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.98653
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.98653
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
29.401026
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
29.401026
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.739382
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.739382
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
30.420074
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
30.420074
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
32.28135
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
32.28135
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
32.68202
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
32.68202
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
32.68202
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
32.68202
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.71571
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.71571
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.311943
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.311943
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.311943
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.311943
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
33.423103
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
33.423103
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
33.423103
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
33.423103
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.121334
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.121334
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
37.588253
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
37.588253
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
37.588253
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
37.588253
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
38.108818
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
38.108818
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.412148
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.412148
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.412148
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.412148
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
38.962326
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
38.962326
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
38.962326
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
38.962326
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
39.74403
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
41.258358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
41.258358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
41.258358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
41.258358
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.951843
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.951843
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
42.44646
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
42.44646
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
42.44646
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
42.44646
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
42.78616
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.785652
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.785652
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.08301
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.08301
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.691933
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.691933
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.691933
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.691933
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
46.28717
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
46.28717
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.663116
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.663116
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.663116
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.663116
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
48.183125
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
48.183125
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.29245
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.375145
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.375145
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.61321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.61321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.61321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.61321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.08185
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.08185
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.08185
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.08185
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.229385
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.229385
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
50.67243
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
50.67243
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
50.826794
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
50.826794
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
51.193356
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
51.193356
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
51.193356
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
51.193356
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.430378
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.430378
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
52.862194
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
52.862194
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
52.862194
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
52.862194
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.140205
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.140205
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.140205
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.140205
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.527245
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.642693
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.642693
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.642693
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.642693
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.816616
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.816616
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
56.487293
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
56.487293
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
56.487293
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
56.487293
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
61.72069
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
61.72069
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
64.95001
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
64.95001
seq distance
False
chain
G
Details
Redox score
66.71
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
8.39
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
105 (Residue 74 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 10 A 44
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.5380576
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.1429887
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.1429887
seq distance
17
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
5.0561533
seq distance
12
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
5.0561533
seq distance
12
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
5.110539
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
5.110539
seq distance
False
chain
B
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
14
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.861765
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.2470374
seq distance
10
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.2470374
seq distance
10
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
13
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
13
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.309887
seq distance
13
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.309887
seq distance
13
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.848803
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.848803
seq distance
3
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.848803
seq distance
3
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.848803
seq distance
3
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.1874394
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.1874394
seq distance
4
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.5996814
seq distance
16
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.5996814
seq distance
16
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.5996814
seq distance
16
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.5996814
seq distance
16
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.551682
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.551682
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.816506
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.816506
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.816506
seq distance
13
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.816506
seq distance
13
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.696992
seq distance
7
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.696992
seq distance
7
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.802341
seq distance
6
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.802341
seq distance
6
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.77106
seq distance
21
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.219311
seq distance
24
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.219311
seq distance
24
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
11.227533
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
11.227533
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
11.227533
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
11.227533
seq distance
22
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.247838
seq distance
7
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.247838
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.583557
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.583557
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.583557
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.583557
seq distance
30
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
12.885228
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
12.885228
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
12.885228
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
12.885228
seq distance
23
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.809057
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.809057
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
14.087921
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
14.087921
seq distance
False
chain
B
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.341695
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.341695
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.341695
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.341695
seq distance
29
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
15.216886
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
15.216886
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
15.216886
seq distance
17
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
15.216886
seq distance
17
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.91223
seq distance
18
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.91223
seq distance
18
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.008213
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
17.9497
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
17.9497
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
17.995367
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.438768
seq distance
41
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
18.53855
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
18.72002
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
19.42964
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
19.42964
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.221546
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
20.764978
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
22.25435
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
22.25435
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
22.34849
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
22.34849
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
22.382446
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
22.382446
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
22.382446
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
22.382446
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
22.899443
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
23.0163
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
23.0163
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
23.267164
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
23.285671
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
23.686863
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
23.888681
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
23.888681
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
24.660248
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.447021
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
25.447021
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
28.723175
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
28.723175
seq distance
False
chain
D
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.901896
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.901896
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.901896
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.901896
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
34.159996
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
34.159996
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
36.762646
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
36.762646
seq distance
False
chain
D
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.92485
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.92485
seq distance
False
chain
C
Details
Redox score
66.66
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
8.24
Half-sphere exposure sum
73
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
41 (Residue 10 in this structure)
Residue number B
75 (Residue 44 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 C 73 C 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7917666
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7917666
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7917666
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7917666
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8432553
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8432553
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8432553
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8432553
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.7747169
seq distance
12
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.7747169
seq distance
12
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.7747169
seq distance
12
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.7747169
seq distance
12
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.452611
seq distance
11
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.452611
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.466126
seq distance
8
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.7219696
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.7219696
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.7219696
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.7219696
seq distance
7
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7677097
seq distance
5
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7677097
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.9713216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.9713216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.9713216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.9713216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.137127
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.137127
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.137127
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.137127
seq distance
45
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.193335
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.55512
seq distance
46
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.55512
seq distance
46
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.914882
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.914882
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.143335
seq distance
37
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.143335
seq distance
37
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.617722
seq distance
50
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.617722
seq distance
50
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.617722
seq distance
50
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.617722
seq distance
50
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.349126
seq distance
52
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.349126
seq distance
52
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.537197
seq distance
16
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.537197
seq distance
16
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.537197
seq distance
16
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.537197
seq distance
16
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.121199
seq distance
53
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.121199
seq distance
53
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.136132
seq distance
17
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.136132
seq distance
17
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.665774
seq distance
49
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.665774
seq distance
49
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.6807375
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.6807375
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.6807375
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.6807375
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.454162
seq distance
59
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.454162
seq distance
59
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.7340145
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.7340145
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.7340145
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.7340145
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.307966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.307966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.829437
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.829437
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.829437
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.829437
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.065371
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.065371
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.065371
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.065371
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.698004
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.698004
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.961822
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.961822
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.436853
seq distance
26
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.436853
seq distance
26
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.436853
seq distance
26
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.436853
seq distance
26
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.573011
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.573011
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.662704
seq distance
56
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.662704
seq distance
56
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
16.856937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.671043
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.671043
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.707775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.707775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.707775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.707775
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.433323
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.433323
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.433323
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.433323
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.698627
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.698627
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
18.811388
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.93137
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.93137
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.93137
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.93137
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.519962
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.519962
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.925684
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.925684
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.107666
seq distance
23
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.107666
seq distance
23
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.13283
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.13283
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.13283
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.13283
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.522593
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.522593
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.522593
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.522593
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.79843
seq distance
22
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.79843
seq distance
22
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.29473
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.29473
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.53012
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.53012
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.849936
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.849936
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.974695
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.974695
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.764874
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.764874
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.743473
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.743473
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.743473
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.743473
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.475513
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.475513
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
36.485394
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
36.485394
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
37.151455
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
37.151455
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
37.348167
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
37.348167
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.792053
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.792053
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
39.506477
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
39.506477
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
39.506477
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
39.506477
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.100315
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.100315
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.486477
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.486477
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.486477
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.486477
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.940098
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.940098
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
42.073673
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
42.073673
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
42.073673
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
42.073673
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
43.8771
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
43.8771
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
44.090504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
44.090504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
44.090504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
44.090504
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
45.55116
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
45.55116
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
45.55116
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
45.55116
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
45.93649
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
46.17157
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
46.17157
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
46.17157
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
46.17157
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.776154
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.776154
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.531506
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.531506
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.531506
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.531506
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
48.583084
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
48.583084
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
48.583084
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
48.583084
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
50.0662
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.9177
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.9177
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
51.227062
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
51.227062
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.038937
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.038937
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.038937
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.038937
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.064846
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.064846
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.606506
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.606506
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.606506
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.606506
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.729668
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.729668
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
56.061676
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.800777
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.800777
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.800777
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.800777
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.895214
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.895214
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.35275
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.35275
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.35275
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.35275
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.2171
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.2171
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.520317
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.520317
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
59.882385
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
59.882385
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.917583
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.917583
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
60.11024
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
60.11024
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
60.11024
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
60.11024
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
60.12531
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
60.12531
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.64999
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.64999
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.64999
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.64999
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.04854
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.04854
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.04854
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.04854
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.362404
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.54272
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.54272
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.54272
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.54272
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.923317
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.923317
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
66.02729
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
66.02729
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
66.02729
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
66.02729
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
71.30497
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
71.30497
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
74.35188
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
74.35188
seq distance
False
chain
G
Details
Redox score
66.57
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
6.79
Half-sphere exposure sum
93
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
104 (Residue 73 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 61 C 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
66.52
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
7.84
Half-sphere exposure sum
73
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
92 (Residue 61 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 13 C 28
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
66.33
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
7.48
Half-sphere exposure sum
87
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
44 (Residue 13 in this structure)
Residue number B
59 (Residue 28 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 C 27 C 28
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7489028
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7489028
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8281596
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8281596
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8281596
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8281596
seq distance
0
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
3.8546982
seq distance
13
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
3.8546982
seq distance
13
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.545027
seq distance
40
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.545027
seq distance
40
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.3539186
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.3539186
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.386956
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.386956
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.782649
seq distance
46
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.782649
seq distance
46
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.782649
seq distance
46
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.782649
seq distance
46
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.425221
seq distance
8
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.425221
seq distance
8
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.43428
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.43428
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.43428
seq distance
45
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.43428
seq distance
45
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.609093
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.609093
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.987643
seq distance
10
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.987643
seq distance
10
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.035617
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.035617
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.035617
seq distance
39
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.035617
seq distance
39
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.515155
seq distance
4
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.515155
seq distance
4
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.515155
seq distance
4
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.515155
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.230346
seq distance
29
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.230346
seq distance
29
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.230346
seq distance
29
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.230346
seq distance
29
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.258106
seq distance
38
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.258106
seq distance
38
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.258106
seq distance
38
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.258106
seq distance
38
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.490019
seq distance
28
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.490019
seq distance
28
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.068797
seq distance
3
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.068797
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.516725
seq distance
37
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.570772
seq distance
57
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.237791
seq distance
19
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.237791
seq distance
19
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.237791
seq distance
19
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.237791
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.909582
seq distance
33
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.909582
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.909582
seq distance
33
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.909582
seq distance
33
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.756865
seq distance
34
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.756865
seq distance
34
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.999698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.999698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.379761
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.379761
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.379761
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.379761
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.60725
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.60725
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.60725
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.60725
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.347915
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.347915
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.347915
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.347915
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.138418
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.138418
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.138418
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.138418
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.380514
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.380514
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.695412
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.695412
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.893398
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.893398
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
17.116703
seq distance
22
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
17.116703
seq distance
22
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.937817
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.937817
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.907564
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.907564
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.907564
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.907564
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.976027
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.07926
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.07926
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.454727
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.454727
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.91349
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.060097
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.060097
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.060097
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.060097
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
20.100363
seq distance
23
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
20.100363
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.046637
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.046637
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.046637
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.046637
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.67869
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.67869
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.856047
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.856047
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.098055
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.098055
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.098055
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.098055
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.953272
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.953272
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.953272
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.953272
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.153675
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.153675
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.518707
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.518707
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.865265
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.865265
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.72697
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.72697
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.671444
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.671444
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.671444
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.671444
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.306988
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.306988
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92415
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92415
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.05329
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.05329
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.918877
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.918877
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.644604
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.644604
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.644604
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.644604
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.807865
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.807865
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.026237
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.026237
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.10063
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.10063
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.10063
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.10063
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.639896
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.639896
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.53255
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.53255
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.53255
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.53255
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.30544
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.30544
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.30544
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.30544
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.55357
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.55357
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.590107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.590107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.590107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.590107
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.549366
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.323338
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.323338
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.323338
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.323338
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
46.308796
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
46.308796
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
46.308796
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
46.308796
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.637604
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.637604
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.148605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.148605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.148605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.148605
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.483833
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.367374
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.367374
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.506264
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.506264
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.06992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.06992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.06992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.06992
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.202244
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.202244
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.444355
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.444355
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.444355
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.444355
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.588432
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.588432
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
56.265823
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.500626
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.500626
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.500626
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.500626
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.92004
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.92004
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.38111
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.38111
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.38111
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.38111
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.189236
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.189236
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.300903
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.300903
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.514656
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.514656
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.660454
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.660454
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.660454
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.660454
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
59.93239
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
59.93239
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.965332
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.965332
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.502064
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.502064
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.502064
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.502064
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
60.923515
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
60.923515
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
60.923515
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
60.923515
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.038414
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.5999
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.5999
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.5999
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.5999
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.865986
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.865986
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.61928
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.61928
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.61928
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.61928
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.827515
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.827515
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.82013
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.82013
seq distance
False
chain
G
Details
Redox score
65.87
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
6.79
Half-sphere exposure sum
103
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
58 (Residue 27 in this structure)
Residue number B
59 (Residue 28 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 21 C 54
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
2.779597
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
2.779597
seq distance
0
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
4.3903217
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
4.3903217
seq distance
False
chain
D
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
5.206009
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
5.206009
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
5.447157
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
5.447157
seq distance
6
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
5.943422
seq distance
7
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
5.943422
seq distance
7
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
5.943422
seq distance
7
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
5.943422
seq distance
7
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
6.5072656
seq distance
2
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
6.5072656
seq distance
2
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
6.5072656
seq distance
2
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
6.5072656
seq distance
2
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
6.6923037
seq distance
2
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
6.6923037
seq distance
2
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.722665
seq distance
3
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.722665
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
7.9080515
seq distance
7
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
7.9080515
seq distance
7
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
7.968803
seq distance
4
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
7.968803
seq distance
4
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
8.286697
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
8.286697
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
8.286697
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
8.286697
seq distance
7
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
9.272072
seq distance
4
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
9.272072
seq distance
4
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
9.279872
seq distance
3
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
9.279872
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.436339
seq distance
3
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.436339
seq distance
3
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.436339
seq distance
3
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.436339
seq distance
3
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.793354
seq distance
15
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.793354
seq distance
15
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.573375
seq distance
14
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
11.573375
seq distance
14
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
12.007153
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
12.007153
seq distance
False
chain
D
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.37188
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.37188
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.37188
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.37188
seq distance
20
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
12.626086
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
12.626086
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
12.626086
seq distance
12
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
12.626086
seq distance
12
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
13.009806
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
14.66863
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
14.66863
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
14.66863
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
14.66863
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.379071
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.379071
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.379071
seq distance
19
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.379071
seq distance
19
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.472155
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
15.472155
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.389917
seq distance
7
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.389917
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.389917
seq distance
7
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.389917
seq distance
7
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.42877
seq distance
8
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.42877
seq distance
8
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.161987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.161987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
19.161987
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
19.161987
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.587729
seq distance
31
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
19.835417
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
19.835417
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
19.835417
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
19.835417
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.86499
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
19.86499
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
20.314938
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
20.314938
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
20.314938
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
20.314938
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
21.132807
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
21.132807
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
21.277433
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
21.277433
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
22.450523
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.863785
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.863785
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.863785
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.863785
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
24.085936
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
24.085936
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
24.188162
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
24.188162
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
24.188162
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
24.188162
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
24.502802
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
24.502802
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.624311
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
24.624311
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
24.842993
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
24.842993
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
25.115122
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
25.115122
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
25.115122
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
25.115122
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
25.6025
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
25.6025
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
25.6025
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
25.6025
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
25.72639
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
25.838015
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
25.838015
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
27.214474
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
27.214474
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
27.214474
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
27.214474
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.687468
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.687468
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
30.394117
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
30.394117
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
30.394117
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
30.394117
seq distance
False
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
30.435312
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
30.435312
seq distance
False
chain
B
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
35.707912
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
35.707912
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
38.24358
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
38.24358
seq distance
False
chain
A
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
38.265438
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
38.265438
seq distance
False
chain
B
Details
Redox score
65.56
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
7.65
Half-sphere exposure sum
81
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
52 (Residue 21 in this structure)
Residue number B
85 (Residue 54 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 A 10 A 13
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.5493248
seq distance
14
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.5493248
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.921464
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.921464
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.1115584
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.1115584
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.7938447
seq distance
1
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.7938447
seq distance
1
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
4.845445
seq distance
43
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
4.845445
seq distance
43
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
5.727813
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
5.727813
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
5.727813
seq distance
15
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
5.727813
seq distance
15
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.6150756
seq distance
10
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.6150756
seq distance
10
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.6150756
seq distance
10
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.6150756
seq distance
10
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.665806
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.665806
seq distance
4
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.9151297
seq distance
34
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.9151297
seq distance
34
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
6.9151297
seq distance
34
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
6.9151297
seq distance
34
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.615903
seq distance
44
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.615903
seq distance
44
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.615903
seq distance
44
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.615903
seq distance
44
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
8.6553135
seq distance
11
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
8.6553135
seq distance
11
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.818173
seq distance
37
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
9.818173
seq distance
37
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.035463
seq distance
23
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
10.035463
seq distance
23
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.490696
seq distance
55
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
10.490696
seq distance
55
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
11.089173
seq distance
53
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
11.089173
seq distance
53
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
11.089173
seq distance
53
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
11.089173
seq distance
53
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.466716
seq distance
61
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.466716
seq distance
61
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.466716
seq distance
61
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.466716
seq distance
61
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.581746
seq distance
38
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
11.581746
seq distance
38
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.647683
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.044302
seq distance
54
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.044302
seq distance
54
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
13.044302
seq distance
54
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
13.044302
seq distance
54
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.426871
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
13.426871
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
14.147114
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
14.147114
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.324973
seq distance
60
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.324973
seq distance
60
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
14.324973
seq distance
60
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
14.324973
seq distance
60
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.201057
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.201057
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.201057
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.201057
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
15.9658575
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
15.9658575
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.042015
seq distance
48
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.042015
seq distance
48
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.042015
seq distance
48
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.042015
seq distance
48
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
16.64801
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
16.64801
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.157055
seq distance
49
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.157055
seq distance
49
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.871202
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.871202
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
17.871202
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
17.871202
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
17.90944
seq distance
72
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.066442
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
18.066442
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.81384
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.81384
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.986818
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.986818
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.987776
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.987776
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
19.31902
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
19.31902
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.064852
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.064852
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
20.164013
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
20.164013
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
20.164013
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
20.164013
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
20.270487
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
20.270487
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
20.270487
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
20.270487
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
20.43364
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
20.43364
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
21.462456
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
21.462456
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
21.947273
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
21.947273
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.352413
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.352413
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.352413
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.352413
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.357475
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.357475
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.357475
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.357475
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
22.471935
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
22.471935
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
22.57101
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
22.57101
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.712818
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.712818
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
22.712818
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
22.712818
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.958448
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.958448
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
22.958448
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
22.958448
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
22.98781
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
22.98781
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
23.04254
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
23.931234
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
23.931234
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
23.931234
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
23.931234
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.223219
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.223219
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
25.124802
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
25.124802
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
25.124802
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
25.124802
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
25.362398
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
25.381552
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
25.381552
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
26.214457
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
26.214457
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
26.214457
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
26.214457
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
26.248447
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
26.248447
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
26.248447
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
26.248447
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
26.29705
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
26.29705
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
26.685919
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
26.685919
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
27.113356
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
27.113356
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
27.172626
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
27.172626
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
27.172626
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
27.172626
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
28.25883
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
28.25883
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
28.25883
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
28.25883
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.48034
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.48034
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
28.48034
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
28.48034
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
28.964712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
28.964712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
28.964712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
28.964712
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
29.322298
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
31.200712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
31.200712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
31.200712
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
31.200712
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
31.846115
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
31.846115
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
31.943245
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
31.943245
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
31.943245
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
31.943245
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
32.807575
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.886745
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
33.886745
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
34.622303
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
34.622303
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
34.67371
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
34.67371
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
34.67651
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
34.67651
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
34.67651
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
34.67651
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
35.743526
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
35.743526
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
36.307465
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
36.307465
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
36.307465
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
36.307465
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
36.456818
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.703293
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
36.703293
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.76191
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.76191
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
37.57529
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
37.57529
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
37.57529
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
37.57529
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.49239
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.49239
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.49239
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.49239
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
38.56489
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
38.56489
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
39.41879
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
39.41879
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
40.120586
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
40.120586
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.930195
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.930195
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.930195
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.930195
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
41.093575
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
41.093575
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
41.218235
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
41.218235
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
41.454052
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
41.454052
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
41.454052
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
41.454052
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
41.653973
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
41.653973
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
41.653973
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
41.653973
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
42.231403
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
42.231403
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
42.231403
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
42.231403
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
42.371086
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
43.706295
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
43.706295
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
46.697254
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
46.697254
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
46.697254
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
46.697254
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
51.960995
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
51.960995
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
55.036327
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
55.036327
seq distance
False
chain
G
Details
Redox score
64.93
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.06
Half-sphere exposure sum
70
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
41 (Residue 10 in this structure)
Residue number B
44 (Residue 13 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 G 28 G 44
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.7181618
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
3.7181618
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.4558845
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.4558845
seq distance
1
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6598935
seq distance
24
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6598935
seq distance
24
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.5238643
seq distance
4
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
5.5238643
seq distance
4
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.0139074
seq distance
5
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.0139074
seq distance
5
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.0139074
seq distance
5
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.0139074
seq distance
5
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.224579
seq distance
30
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.224579
seq distance
30
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.224579
seq distance
30
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.224579
seq distance
30
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.337027
seq distance
8
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
6.337027
seq distance
8
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.064864
seq distance
8
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.064864
seq distance
8
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.6068077
seq distance
29
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.6068077
seq distance
29
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.6068077
seq distance
29
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.6068077
seq distance
29
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.7517333
seq distance
3
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.7517333
seq distance
3
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.7517333
seq distance
3
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.7517333
seq distance
3
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.904951
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.904951
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.9525976
seq distance
14
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
7.9525976
seq distance
14
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.197473
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.197473
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.197473
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.197473
seq distance
23
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.957195
seq distance
13
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.957195
seq distance
13
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.957195
seq distance
13
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.957195
seq distance
13
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.441611
seq distance
12
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.441611
seq distance
12
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.441894
seq distance
22
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.441894
seq distance
22
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.441894
seq distance
22
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.441894
seq distance
22
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
10.161729
seq distance
11
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
10.161729
seq distance
11
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.038317
seq distance
21
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.093465
seq distance
41
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.915324
seq distance
6
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
12.915324
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.959577
seq distance
17
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.959577
seq distance
17
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.959577
seq distance
17
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.959577
seq distance
17
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.034312
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.034312
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
14.1160145
seq distance
18
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
14.1160145
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
16.00821
seq distance
7
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
16.00821
seq distance
7
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.555626
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.555626
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.650429
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.650429
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.227146
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.227146
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
18.007975
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
18.007975
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.46072
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.46072
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.899906
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.047613
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.047613
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.812206
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.812206
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20287
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20287
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.687754
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.687754
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.192972
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.192972
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.486967
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.486967
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.22533
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.22533
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.309616
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.309616
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92471
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92471
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.15875
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.15875
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.995155
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.995155
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.74589
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.74589
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.092915
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.092915
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.67442
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.67442
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.93187
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.93187
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.906048
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.906048
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.08933
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.08933
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.46633
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.46633
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.081528
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.081528
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.399197
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.399197
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.975525
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.975525
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.19118
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.19118
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.569088
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.569088
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.773453
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.773453
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.825214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.825214
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
60.135727
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
60.135727
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.922493
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.922493
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.62415
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.62415
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.58179
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.58179
seq distance
False
chain
C
Details
Redox score
64.82
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
8.71
Half-sphere exposure sum
87
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
75 (Residue 44 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 44 C 54
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
64.62
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
9.07
Half-sphere exposure sum
70
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
75 (Residue 44 in this structure)
Residue number B
85 (Residue 54 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 C 61 C 79
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8045402
seq distance
0
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4073315
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6079075
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6079075
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6079075
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6079075
seq distance
6
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
3.9803421
seq distance
4
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.060974
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.102786
seq distance
6
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.8360195
seq distance
1
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.8360195
seq distance
1
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4113054
seq distance
25
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4113054
seq distance
25
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.63216
seq distance
6
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.9176965
seq distance
7
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.9176965
seq distance
7
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.170532
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.170532
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.253449
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.253449
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.253449
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.253449
seq distance
33
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.583399
seq distance
34
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.583399
seq distance
34
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.510868
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.510868
seq distance
38
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.510868
seq distance
38
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.510868
seq distance
38
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.85521
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.85521
seq distance
40
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.931552
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.994541
seq distance
37
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.994541
seq distance
37
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.202342
seq distance
41
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.202342
seq distance
41
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.611685
seq distance
4
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.708506
seq distance
5
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.708506
seq distance
5
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
12.031949
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.8436775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.8436775
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.167935
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.65131
seq distance
47
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.65131
seq distance
47
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.094285
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.271904
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
14.271904
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.977096
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.977096
seq distance
14
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.977096
seq distance
14
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.977096
seq distance
14
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.114609
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.117569
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.117569
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.640722
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.167656
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.17937
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.17937
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.328785
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
16.328785
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.92295
seq distance
44
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.92295
seq distance
44
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
17.104794
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.401669
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.401669
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.553038
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.778835
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.778835
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.417534
seq distance
11
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.417534
seq distance
11
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.97248
seq distance
10
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.97248
seq distance
10
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
20.15687
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.31582
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.31582
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.835161
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.835161
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
23.5069
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.808535
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.808535
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.386211
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.386211
seq distance
False
chain
A
Details
Redox score
64.37
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
9.16
Half-sphere exposure sum
73
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
92 (Residue 61 in this structure)
Residue number B
110 (Residue 79 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 G 34 G 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.8276207
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.494897
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.494897
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.494897
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.494897
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.0146055
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.0146055
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.0146055
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.0146055
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.3652453
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.3652453
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.3652453
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.3652453
seq distance
12
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7661138
seq distance
17
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7661138
seq distance
17
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.6059084
seq distance
24
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.6059084
seq distance
24
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.6059084
seq distance
24
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.6059084
seq distance
24
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.168048
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.168048
seq distance
7
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.3135734
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.3135734
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.3622684
seq distance
11
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.3622684
seq distance
11
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.3622684
seq distance
11
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.3622684
seq distance
11
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
6.365697
seq distance
19
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
6.365697
seq distance
19
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
6.365697
seq distance
19
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
6.365697
seq distance
19
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.301882
seq distance
2
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.301882
seq distance
2
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.8370056
seq distance
23
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.8370056
seq distance
23
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
8.461675
seq distance
20
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.064113
seq distance
14
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.064113
seq distance
14
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.149471
seq distance
13
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.149471
seq distance
13
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.638317
seq distance
23
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.638317
seq distance
23
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.638317
seq distance
23
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.638317
seq distance
23
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.241111
seq distance
11
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.241111
seq distance
11
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.241111
seq distance
11
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.241111
seq distance
11
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.033638
seq distance
22
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.033638
seq distance
22
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.19279
seq distance
20
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.19279
seq distance
20
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.665223
seq distance
10
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.665223
seq distance
10
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.729977
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.729977
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.713982
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.713982
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.713982
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.713982
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.918107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.918107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.918107
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.918107
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.206302
seq distance
17
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.206302
seq distance
17
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.632386
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.632386
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.726875
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.726875
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.726875
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.726875
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.076457
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.076457
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.076457
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.076457
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.995718
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.995718
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.206665
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.206665
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.531439
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.531439
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
17.190649
seq distance
13
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
17.190649
seq distance
13
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
17.190649
seq distance
13
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
17.190649
seq distance
13
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.230919
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.230919
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.230919
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.230919
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.259386
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.259386
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.367018
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.139366
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.139366
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.139366
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.139366
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.580214
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.580214
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.046806
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.573421
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.573421
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.762695
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.762695
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.762695
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.762695
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.875896
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.875896
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.875896
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.875896
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.201586
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.201586
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.620173
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.620173
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.620173
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.620173
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.94667
seq distance
16
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.94667
seq distance
16
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.145386
seq distance
17
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.145386
seq distance
17
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.825073
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.825073
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
27.319014
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
27.319014
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.634146
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.634146
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.355133
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.355133
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
31.40575
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
31.40575
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
31.40575
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
31.40575
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
33.067356
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
33.067356
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
34.546867
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
34.546867
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
34.774715
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
34.774715
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
35.47471
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
35.47471
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
36.947052
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
36.947052
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
36.947052
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
36.947052
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
37.38825
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
37.38825
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
38.36713
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
38.36713
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
38.70662
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
38.70662
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
38.70662
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
38.70662
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
39.200554
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
39.200554
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
40.198593
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
40.198593
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
40.198593
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
40.198593
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
41.630375
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
41.630375
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
41.630375
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
41.630375
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
41.64333
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
41.64333
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
42.925472
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
42.925472
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
42.925472
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
42.925472
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
43.35139
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
43.992355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
43.992355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
43.992355
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
43.992355
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
45.34473
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
45.34473
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
46.003307
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
46.003307
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
46.003307
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
46.003307
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
46.378315
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
46.378315
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
46.378315
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
46.378315
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.016636
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
48.709675
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
48.709675
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
49.0817
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
49.0817
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
53.502686
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
53.502686
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
53.502686
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
53.502686
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
53.719643
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
53.719643
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
53.966507
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
53.966507
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
54.16799
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
54.16799
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
54.16799
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
54.16799
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
55.012154
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
55.012154
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
55.012154
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
55.012154
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
55.243073
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
55.34405
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
55.34405
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
57.095745
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
57.095745
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
57.095745
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
57.095745
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
57.88393
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
57.88393
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
57.887653
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
57.887653
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
58.01536
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
58.01536
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
58.01536
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
58.01536
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
58.38082
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
58.38082
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
58.39734
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
58.39734
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
58.65562
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
58.65562
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
59.199406
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
59.199406
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
59.199406
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
59.199406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
59.678825
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
59.678825
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
59.678825
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
59.678825
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
59.7147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
61.358463
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
61.358463
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
61.358463
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
61.358463
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
62.374264
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
62.374264
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
63.98242
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
63.98242
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
63.98242
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
63.98242
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
69.35538
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
69.35538
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
72.28499
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
72.28499
seq distance
False
chain
C
Details
Redox score
64.24
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.24
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
65 (Residue 34 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 E 67 E 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.7934093
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.7934093
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
2.7934093
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
2.7934093
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8466444
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8466444
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8466444
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8466444
seq distance
0
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
3.4575045
seq distance
11
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.5673327
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.5673327
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.5673327
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.5673327
seq distance
1
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.711376
seq distance
1
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.711376
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.9750504
seq distance
6
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.9750504
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.9750504
seq distance
6
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.9750504
seq distance
6
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.274306
seq distance
1
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.274306
seq distance
1
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.274306
seq distance
1
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.274306
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.45421
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.45421
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.45421
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.45421
seq distance
39
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.6442337
seq distance
2
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.8217573
seq distance
40
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.8217573
seq distance
40
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.9209266
seq distance
5
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.9209266
seq distance
5
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.03751
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.03751
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.171816
seq distance
10
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.171816
seq distance
10
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.171816
seq distance
10
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.171816
seq distance
10
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.218085
seq distance
31
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
8.218085
seq distance
31
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.87185
seq distance
44
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.87185
seq distance
44
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.87185
seq distance
44
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.87185
seq distance
44
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.476746
seq distance
46
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.476746
seq distance
46
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.934359
seq distance
11
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.934359
seq distance
11
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.431608
seq distance
47
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
10.431608
seq distance
47
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.865474
seq distance
43
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
11.865474
seq distance
43
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.942321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.942321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.942321
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.942321
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.945029
seq distance
53
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.945029
seq distance
53
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.951004
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.951004
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.951004
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.951004
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.273267
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.273267
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.990824
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.990824
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.990824
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.990824
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.226021
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.226021
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.226021
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.226021
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.651195
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.651195
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.034939
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.034939
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.406347
seq distance
50
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.406347
seq distance
50
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.607313
seq distance
20
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.607313
seq distance
20
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.607313
seq distance
20
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.607313
seq distance
20
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.543835
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.648808
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.648808
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.776098
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.776098
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.776098
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.776098
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.875889
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.875889
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.49065
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.49065
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.49065
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.49065
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.84591
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
18.84591
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.37622
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.37622
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.388166
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.442965
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.442965
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
19.442965
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
19.442965
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.945482
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.945482
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.945482
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.945482
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.12111
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.12111
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.138063
seq distance
17
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.138063
seq distance
17
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.652649
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.652649
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.652649
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.652649
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.995354
seq distance
16
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.995354
seq distance
16
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.446465
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.446465
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.229847
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.229847
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.580523
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
24.580523
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.630392
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.630392
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.379417
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.379417
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.379417
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.379417
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.663715
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.663715
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
28.227497
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
28.227497
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.880596
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.880596
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
29.535997
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
29.535997
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.897572
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.897572
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
30.613413
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
30.613413
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
32.263485
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
32.263485
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.7549
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.7549
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
32.833294
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
32.833294
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
32.833294
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
32.833294
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
33.450157
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
33.450157
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
33.450157
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
33.450157
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.56252
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.56252
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.56252
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.56252
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.208607
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
36.208607
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
37.820873
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
37.820873
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
37.820873
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
37.820873
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
38.308304
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
38.308304
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.323177
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.323177
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
38.323177
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
38.323177
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.05303
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.05303
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.05303
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.05303
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
39.757042
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
41.079647
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
41.079647
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
41.079647
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
41.079647
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.868916
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
41.868916
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
42.25305
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
42.99878
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
42.99878
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
42.99878
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
42.99878
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
43.402863
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
43.402863
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.112034
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.112034
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.56797
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.56797
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.56797
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.56797
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
45.92036
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
45.92036
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
47.214638
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
47.214638
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.001774
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.001774
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.001774
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.001774
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
48.1446
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
48.1446
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.61233
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.61233
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.61233
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.61233
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.99149
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
49.943695
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
49.943695
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
50.20608
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
50.20608
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.400528
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.400528
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.400528
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.400528
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
50.58057
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
50.58057
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
50.89276
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
50.89276
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
50.89276
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
50.89276
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.81874
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.81874
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
53.152878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
53.152878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
53.152878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
53.152878
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.587296
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.587296
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.587296
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.587296
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.684086
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.960144
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.960144
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.960144
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.960144
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.79955
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.79955
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
55.322773
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
55.322773
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
55.322773
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
55.322773
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
60.349274
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
60.349274
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
63.81629
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
63.81629
seq distance
False
chain
C
Details
Redox score
64.04
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
8.7
Half-sphere exposure sum
84
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
98 (Residue 67 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 73 A 79
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7599833
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.5846667
seq distance
12
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.5846667
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.5846667
seq distance
12
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.5846667
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.972913
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.972913
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.972913
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.972913
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.2514434
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.2514434
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.2514434
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.2514434
seq distance
7
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.348892
seq distance
11
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.348892
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.8326116
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.8326116
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
4.8326116
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
4.8326116
seq distance
6
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.160844
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1468577
seq distance
37
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1468577
seq distance
37
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.700962
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.700962
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8414574
seq distance
45
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8414574
seq distance
45
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
6.8414574
seq distance
45
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
6.8414574
seq distance
45
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
7.0169873
seq distance
5
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
7.0169873
seq distance
5
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.3470736
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.442004
seq distance
46
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.442004
seq distance
46
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441045
seq distance
50
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441045
seq distance
50
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.441045
seq distance
50
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.441045
seq distance
50
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.46922
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.46922
seq distance
52
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.090286
seq distance
16
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.090286
seq distance
16
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.090286
seq distance
16
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.090286
seq distance
16
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.688666
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.688666
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.688666
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.688666
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.716887
seq distance
49
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.716887
seq distance
49
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.028416
seq distance
53
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.028416
seq distance
53
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.182835
seq distance
17
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.182835
seq distance
17
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.674757
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.674757
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.674757
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.674757
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.52144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.52144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.682919
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.682919
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.682919
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.682919
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.256284
seq distance
59
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.256284
seq distance
59
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.486598
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.486598
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
13.854504
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
13.854504
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
13.854504
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
13.854504
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
14.000779
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
14.000779
seq distance
False
chain
B
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.6559725
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.6559725
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.12082
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.2753525
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.2753525
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.381961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.381961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.381961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.381961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
15.825045
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
15.825045
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.008224
seq distance
26
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.008224
seq distance
26
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.008224
seq distance
26
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.008224
seq distance
26
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.411268
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.411268
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.411268
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.411268
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.681791
seq distance
56
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
16.681791
seq distance
56
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.75214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.954666
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.954666
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
16.954666
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
16.954666
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
17.042967
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
17.042967
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
17.416481
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
17.416481
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
18.78142
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
18.78142
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
18.787203
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
18.787203
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
18.787203
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
18.787203
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
19.88318
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
19.88318
seq distance
False
chain
D
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.86798
seq distance
23
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.86798
seq distance
23
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.416489
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.416489
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.416489
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.416489
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.641459
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.641459
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.539845
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.539845
seq distance
False
chain
B
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.674267
seq distance
22
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.674267
seq distance
22
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.481016
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.481016
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.131966
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.131966
seq distance
False
chain
D
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.726732
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.726732
seq distance
False
chain
C
Details
Redox score
63.89
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
8.19
Half-sphere exposure sum
92
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
104 (Residue 73 in this structure)
Residue number B
110 (Residue 79 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 A 79 A 85
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
2.7859986
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.3135967
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.3135967
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.3135967
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.3135967
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.7464862
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.7464862
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
3.7464862
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
3.7464862
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.237311
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.237311
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.237311
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.237311
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.1655383
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.1655383
seq distance
18
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
5.1655383
seq distance
18
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
5.1655383
seq distance
18
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.7542157
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.7542157
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.7542157
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.7542157
seq distance
13
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.3584523
seq distance
11
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.3584523
seq distance
11
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4559407
seq distance
43
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.4559407
seq distance
43
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.203009
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.203009
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.2914224
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.2914224
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
7.2914224
seq distance
51
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
7.2914224
seq distance
51
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.306356
seq distance
17
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
7.306356
seq distance
17
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.646759
seq distance
14
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.830996
seq distance
52
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
7.830996
seq distance
52
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.282802
seq distance
56
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.282802
seq distance
56
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.282802
seq distance
56
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.282802
seq distance
56
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.182537
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.182537
seq distance
22
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.182537
seq distance
22
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.182537
seq distance
22
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.911966
seq distance
58
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.911966
seq distance
58
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.906474
seq distance
55
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.906474
seq distance
55
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.989024
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.989024
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
10.989024
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
10.989024
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.394236
seq distance
59
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
11.394236
seq distance
59
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.596745
seq distance
23
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.596745
seq distance
23
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.963709
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.963709
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.963709
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.963709
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.850961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.850961
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.982866
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.982866
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
12.982866
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
12.982866
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.848693
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.848693
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.862775
seq distance
65
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
13.862775
seq distance
65
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
13.891881
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
13.891881
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
13.891881
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
13.891881
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.955114
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.955114
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.617766
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.63902
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.63902
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.63902
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.63902
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.7035885
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.7035885
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.211521
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.211521
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.317974
seq distance
32
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.317974
seq distance
32
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.317974
seq distance
32
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.317974
seq distance
32
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.568636
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.568636
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.568636
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.568636
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.987135
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
17.070215
seq distance
62
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
17.070215
seq distance
62
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.289375
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.289375
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.289375
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.289375
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.491835
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.491835
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.832125
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.832125
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
19.06135
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
19.06135
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
19.06135
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
19.06135
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
19.220736
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
19.220736
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.074533
seq distance
29
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.074533
seq distance
29
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.72227
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.72227
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.72227
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.72227
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.543457
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.543457
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.119646
seq distance
28
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.119646
seq distance
28
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.712622
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
23.712622
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.76799
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.76799
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
26.017338
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
26.017338
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.363617
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.363617
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.363617
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.363617
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.918238
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.918238
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.96175
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.96175
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
29.132559
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
29.132559
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
30.230103
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
30.230103
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
30.24696
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
30.24696
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
31.083586
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
31.083586
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
33.293285
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
33.293285
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
33.311718
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
33.311718
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
33.445496
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
33.445496
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
33.445496
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
33.445496
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.923946
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.923946
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
33.923946
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
33.923946
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
34.509747
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
34.509747
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
34.509747
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
34.509747
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
37.06964
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
37.06964
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
38.26702
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
38.26702
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
38.26702
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
38.26702
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
39.088856
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
39.088856
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
39.265358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
39.265358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
39.265358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
39.265358
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.72279
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.72279
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.72279
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.72279
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
40.3153
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
42.089504
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
42.089504
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
42.089504
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
42.089504
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
43.0874
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
43.0874
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
43.0874
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
43.0874
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
43.100624
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
43.100624
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
43.738922
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.785652
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.785652
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.68939
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
45.68939
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
46.845463
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
46.845463
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
46.845463
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
46.845463
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
47.40138
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
47.40138
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.375145
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.375145
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.459213
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.459213
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
48.459213
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
48.459213
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.977623
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
49.152866
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
49.152866
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
49.507236
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
49.507236
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
49.507236
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
49.507236
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.93145
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.93145
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.93145
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.93145
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.971355
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.971355
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
51.662163
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
51.662163
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
52.06185
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
52.06185
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
52.34107
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
52.34107
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
52.34107
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
52.34107
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
53.0478
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
53.0478
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
53.722176
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
53.722176
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
53.722176
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
53.722176
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.8281
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.8281
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.8281
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.8281
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
54.336338
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
54.66469
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
54.66469
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
54.66469
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
54.66469
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
55.923084
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
55.923084
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
57.06076
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
57.06076
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
57.06076
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
57.06076
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
62.1281
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
62.1281
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
65.590454
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
65.590454
seq distance
False
chain
G
Details
Redox score
63.8
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.99
Half-sphere exposure sum
nan
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
110 (Residue 79 in this structure)
Residue number B
116 (Residue 85 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 E 13 E 34
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.487924
seq distance
7
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
3.487924
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.648842
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
3.648842
seq distance
7
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.009059
seq distance
8
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
4.009059
seq distance
8
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.838084
seq distance
34
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.838084
seq distance
34
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.9128857
seq distance
1
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.9128857
seq distance
1
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1647477
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1647477
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.3724833
seq distance
40
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.3724833
seq distance
40
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.3724833
seq distance
40
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.3724833
seq distance
40
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.6758556
seq distance
4
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
6.6758556
seq distance
4
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.1829414
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.1829414
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.1829414
seq distance
39
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.1829414
seq distance
39
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.3162026
seq distance
2
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.3162026
seq distance
2
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.96356
seq distance
33
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.96356
seq distance
33
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
7.96356
seq distance
33
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
7.96356
seq distance
33
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.76568
seq distance
10
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.76568
seq distance
10
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.76568
seq distance
10
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.76568
seq distance
10
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.478259
seq distance
10
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.478259
seq distance
10
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.499675
seq distance
22
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.499675
seq distance
22
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.669806
seq distance
32
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.669806
seq distance
32
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.669806
seq distance
32
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.669806
seq distance
32
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.080101
seq distance
23
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.080101
seq distance
23
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.080101
seq distance
23
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.080101
seq distance
23
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
10.581826
seq distance
13
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
10.581826
seq distance
13
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
10.581826
seq distance
13
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
10.581826
seq distance
13
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
10.957258
seq distance
31
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
11.008558
seq distance
51
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.619464
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.619464
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.721868
seq distance
27
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.721868
seq distance
27
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.721868
seq distance
27
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.721868
seq distance
27
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.628069
seq distance
28
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
13.628069
seq distance
28
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.650779
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.650779
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
15.386825
seq distance
16
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
15.386825
seq distance
16
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.929674
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.929674
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
16.135391
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
16.135391
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.194613
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.194613
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.387339
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.387339
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
17.27278
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
17.27278
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
17.524746
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
17.524746
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.908106
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.908106
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
17.9665
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
17.9665
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
17.9665
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
17.9665
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
18.506855
seq distance
17
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
18.506855
seq distance
17
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.892561
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.926186
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.926186
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.960466
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.960466
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.285307
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.285307
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
20.293478
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
20.293478
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.709297
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.709297
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.971811
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.971811
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.971811
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.971811
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.02584
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.02584
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
21.6796
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
21.6796
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.468594
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.468594
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.468594
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.468594
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
23.65148
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
23.65148
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
24.301157
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
24.301157
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
24.338509
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
24.338509
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
24.338509
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
24.338509
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
24.481632
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
24.481632
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
24.481632
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
24.481632
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
26.411537
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
26.411537
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.61029
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.61029
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
27.425135
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
27.425135
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
27.425135
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
27.425135
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
28.18365
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
28.18365
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
28.18365
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
28.18365
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
29.184633
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
29.184633
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
29.184633
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
29.184633
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.205795
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.205795
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
29.41448
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
30.061935
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
30.061935
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
31.109083
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
31.109083
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
31.109083
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
31.109083
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
32.27447
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
32.526127
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
32.526127
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
32.526127
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
32.526127
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
33.34108
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
33.34108
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
34.7556
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
34.7556
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
38.05059
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
38.05059
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
38.05059
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
38.05059
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.086468
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.086468
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
38.253365
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
38.253365
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
39.514893
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
39.514893
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
39.514893
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
39.514893
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.94756
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.94756
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
39.94756
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
39.94756
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
40.32236
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
40.32236
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
41.269848
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
42.087036
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
42.087036
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
42.336662
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
42.336662
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
42.336662
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
42.336662
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
42.419144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
42.419144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
42.419144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
42.419144
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
42.669136
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
42.669136
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
42.99154
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
42.99154
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
43.088654
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
43.088654
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
43.749435
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
43.749435
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
44.833878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
44.833878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
44.833878
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
44.833878
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.875225
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
44.96651
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
44.96651
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
44.96651
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
44.96651
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
46.260147
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
46.260147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
46.260147
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
46.260147
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
46.971626
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
46.971626
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
48.09087
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
48.09087
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
48.09087
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
48.09087
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
53.455402
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
53.455402
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
56.422367
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
56.422367
seq distance
False
chain
C
Details
Redox score
63.47
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
8.93
Half-sphere exposure sum
88
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
44 (Residue 13 in this structure)
Residue number B
65 (Residue 34 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 27 A 34
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
No relevant regions found.
Details
Redox score
63.03
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
8.17
Half-sphere exposure sum
106
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
58 (Residue 27 in this structure)
Residue number B
65 (Residue 34 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 G 21 G 28
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.7670329
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
2.7670329
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.8337514
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.4558845
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.4558845
seq distance
1
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6598935
seq distance
40
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6598935
seq distance
40
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.0316315
seq distance
1
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
5.0316315
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.224579
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.224579
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
6.224579
seq distance
46
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
6.224579
seq distance
46
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.592016
seq distance
2
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.592016
seq distance
2
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
6.592016
seq distance
2
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
6.592016
seq distance
2
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.730796
seq distance
3
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
6.730796
seq distance
3
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.064864
seq distance
8
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.064864
seq distance
8
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.159822
seq distance
19
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.159822
seq distance
19
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
7.159822
seq distance
19
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
7.159822
seq distance
19
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.6068077
seq distance
45
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.6068077
seq distance
45
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
7.6068077
seq distance
45
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
7.6068077
seq distance
45
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.904951
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.904951
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
8.027701
seq distance
7
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
8.027701
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.197473
seq distance
39
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.197473
seq distance
39
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.197473
seq distance
39
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.197473
seq distance
39
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
8.829737
seq distance
28
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
8.829737
seq distance
28
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.957195
seq distance
29
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.957195
seq distance
29
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.957195
seq distance
29
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.957195
seq distance
29
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.200615
seq distance
4
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
9.200615
seq distance
4
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.441894
seq distance
38
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.441894
seq distance
38
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.441894
seq distance
38
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.441894
seq distance
38
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
11.038317
seq distance
37
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
11.996274
seq distance
22
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
11.996274
seq distance
22
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.093465
seq distance
57
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.959577
seq distance
33
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.959577
seq distance
33
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
12.959577
seq distance
33
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
12.959577
seq distance
33
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.034312
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
14.034312
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
14.1160145
seq distance
34
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
14.1160145
seq distance
34
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.596473
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.832032
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.02439
seq distance
23
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
15.02439
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.528812
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.461334
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.555626
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.555626
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.650429
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.650429
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.227146
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.227146
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
18.007975
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
18.007975
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.743248
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
19.294624
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.46072
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.46072
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.96504
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.01235
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.047613
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
20.047613
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
21.274246
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.812206
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.812206
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.814348
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20287
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20287
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.45791
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.687754
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.687754
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.192972
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.192972
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.486967
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
29.486967
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.22533
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
31.22533
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
33.166653
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.309616
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
34.309616
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92471
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.92471
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.15875
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.15875
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.995155
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.995155
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
38.199017
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.74589
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
38.74589
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.092915
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
40.092915
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
40.350094
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.67442
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
40.67442
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
41.552364
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.93187
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.93187
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.94878
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
44.162327
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.776234
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.442146
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.906048
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
46.906048
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.34917
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.66432
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
48.14457
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.08933
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.08933
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.46633
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
50.46633
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
55.027378
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.081528
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
55.081528
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.399197
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
55.399197
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
55.838318
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
56.600574
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.975525
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
56.975525
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
57.022903
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
58.78466
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.19118
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
59.19118
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
59.416744
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.569088
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.569088
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.773453
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
59.773453
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.825214
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
59.825214
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
60.135727
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
60.135727
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.916035
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
61.330406
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
61.33147
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
62.97996
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.922493
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
63.922493
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
65.267395
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.62415
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
70.62415
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.58179
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
73.58179
seq distance
False
chain
C
Details
Redox score
62.98
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.11
Half-sphere exposure sum
96
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
52 (Residue 21 in this structure)
Residue number B
59 (Residue 28 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo A 28 A 61
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.7985404
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.7985404
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.7985404
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.7985404
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8127913
seq distance
0
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8127913
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8127913
seq distance
0
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8127913
seq distance
0
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.2910347
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.2910347
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.2910347
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.2910347
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.4315646
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.4315646
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.4315646
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.4315646
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6381981
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6381981
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6381981
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6381981
seq distance
12
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7775264
seq distance
7
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.7775264
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.7858114
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.7858114
seq distance
1
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.28904
seq distance
1
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.28904
seq distance
1
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
5.5994334
seq distance
4
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.933021
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.933021
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.933021
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.933021
seq distance
13
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
6.050063
seq distance
24
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.036782
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.036782
seq distance
8
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.091034
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.091034
seq distance
7
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.452925
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.452925
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.534322
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.534322
seq distance
8
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.641676
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.641676
seq distance
5
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.641676
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.641676
seq distance
5
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.78426
seq distance
4
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.78426
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
8.78426
seq distance
4
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
8.78426
seq distance
4
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.547948
seq distance
5
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.547948
seq distance
5
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.012681
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.012681
seq distance
14
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.942944
seq distance
4
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.942944
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.906863
seq distance
11
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.906863
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.650808
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.650808
seq distance
False
chain
C
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.901912
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.901912
seq distance
False
chain
B
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.200298
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.200298
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.200298
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.200298
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.239524
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.239524
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.239524
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.239524
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.782452
seq distance
14
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.782452
seq distance
14
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.782452
seq distance
14
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.782452
seq distance
14
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.281124
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.281124
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.281124
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.281124
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
16.034643
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
16.034643
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
16.034643
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
16.034643
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.040215
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.040215
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.249329
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.249329
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
16.83494
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
16.83494
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
17.478971
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
17.478971
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.630642
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.630642
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.630642
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.630642
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.899971
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
18.93806
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
18.93806
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.349146
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.349146
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.687792
seq distance
11
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.687792
seq distance
11
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.921228
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.921228
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.921228
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.921228
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.959248
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.861008
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.861008
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.861008
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.861008
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.43464
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
21.43464
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.684116
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.684116
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.684116
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.684116
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.838583
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
21.838583
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.85269
seq distance
10
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.85269
seq distance
10
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.336985
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
22.336985
seq distance
False
chain
D
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.727604
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.727604
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.727604
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.727604
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
23.129326
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
23.129326
seq distance
False
chain
B
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.92824
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.92824
seq distance
False
chain
C
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
28.411207
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
28.411207
seq distance
False
chain
D
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.525112
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.525112
seq distance
False
chain
C
Details
Redox score
62.55
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
9.97
Half-sphere exposure sum
79
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
92 (Residue 61 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1jk6 A 34 A 61
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8249767
seq distance
0
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8249767
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
2.8249767
seq distance
0
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
2.8249767
seq distance
0
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4040647
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4040647
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
3.4040647
seq distance
5
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
3.4040647
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6103234
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6103234
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
3.6103234
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
3.6103234
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.8125098
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.8125098
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
3.8125098
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
3.8125098
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.08048
seq distance
6
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.232756
seq distance
4
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
5.073697
seq distance
7
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
5.073697
seq distance
7
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.153522
seq distance
1
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
5.153522
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.704581
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.704581
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
5.704581
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
5.704581
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1930623
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1930623
seq distance
7
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.2931514
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.2931514
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
6.4730506
seq distance
24
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.501351
seq distance
2
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.501351
seq distance
2
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.119647
seq distance
13
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.119647
seq distance
13
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.177613
seq distance
14
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.177613
seq distance
14
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.078655
seq distance
11
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.078655
seq distance
11
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.078655
seq distance
11
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.078655
seq distance
11
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.136065
seq distance
20
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.136065
seq distance
20
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.581464
seq distance
5
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
11.581464
seq distance
5
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.667991
seq distance
4
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.667991
seq distance
4
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.667991
seq distance
4
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.667991
seq distance
4
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.569914
seq distance
10
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.569914
seq distance
10
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.726713
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.726713
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.683812
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.683812
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.683812
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.683812
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.795408
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.795408
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.795408
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.795408
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.030176
seq distance
17
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
14.030176
seq distance
17
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.767627
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.767627
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.832457
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.832457
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.832457
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.832457
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.209472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.209472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.209472
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.209472
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.901249
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.901249
seq distance
13
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
15.901249
seq distance
13
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
15.901249
seq distance
13
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.124249
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.124249
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.298412
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.298412
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.48858
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.48858
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.088799
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.088799
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.418428
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.418428
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.418428
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.418428
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.491564
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.912352
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.912352
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.912352
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.912352
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.71225
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
19.71225
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
19.9719
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
63.63636363636363
distance
20.13125
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.313969
seq distance
11
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
20.313969
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.95895
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.95895
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.95895
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.95895
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.038082
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.038082
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.20498
seq distance
10
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
21.20498
seq distance
10
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
22.984386
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
22.984386
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.97525
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.97525
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
25.390451
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
25.390451
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
25.390451
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
25.390451
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.11523
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
26.11523
seq distance
False
chain
C
Details
Redox score
62.47
PDB code
1jk6
Structure name
uncomplexed des 1-6 bovine neurophysin
Structure deposition date
2001-07-11
Thiol separation (Å)
9.9
Half-sphere exposure sum
78
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
65 (Residue 34 in this structure)
Residue number B
92 (Residue 61 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
1npo C 27 C 74
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.723414
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.723414
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8321047
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8321047
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
2.8321047
seq distance
0
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
2.8321047
seq distance
0
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
3.862629
seq distance
13
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
90.9090909090909
distance
3.862629
seq distance
13
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.489258
seq distance
6
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.489258
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.7156153
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.7156153
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
4.7156153
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
4.7156153
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.7194543
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.7194543
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.7194543
seq distance
1
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.7194543
seq distance
1
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
5.0702863
seq distance
7
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
90.9090909090909
distance
5.0702863
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
5.3915935
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
90.9090909090909
distance
5.3915935
seq distance
6
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
6.758792
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
6.758792
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
6.758792
seq distance
7
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
6.758792
seq distance
7
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
7.3354654
seq distance
10
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
90.9090909090909
distance
7.3354654
seq distance
10
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.729623
seq distance
9
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.729623
seq distance
9
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
7.735106
seq distance
8
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
7.735106
seq distance
8
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
7.735106
seq distance
8
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
7.735106
seq distance
8
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
7.862934
seq distance
9
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.946519
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.946519
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
8.6361
seq distance
4
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
8.6361
seq distance
4
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
90.9090909090909
distance
8.6361
seq distance
4
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
90.9090909090909
distance
8.6361
seq distance
4
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.429494
seq distance
17
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.429494
seq distance
17
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.429494
seq distance
17
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.429494
seq distance
17
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.84074
seq distance
18
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.84074
seq distance
18
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.006919
seq distance
3
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.006919
seq distance
3
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
10.24746
seq distance
11
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
10.293941
seq distance
13
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
10.293941
seq distance
13
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
10.293941
seq distance
13
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
10.293941
seq distance
13
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
10.487939
seq distance
12
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
10.487939
seq distance
12
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.014242
seq distance
20
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.014242
seq distance
20
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.014242
seq distance
20
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.014242
seq distance
20
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.455198
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.455198
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
12.455198
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
12.455198
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.695021
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.695021
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
13.695021
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
13.695021
seq distance
False
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.740936
seq distance
False
chain
D
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
13.740936
seq distance
False
chain
D
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.921077
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.921077
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.469528
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.469528
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.469528
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.469528
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.02614
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.02614
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
15.02614
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
15.02614
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.267554
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.267554
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.988206
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.988206
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.593569
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.593569
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
16.868492
seq distance
23
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
16.868492
seq distance
23
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.122486
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.122486
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
17.34951
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.466015
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.466015
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.556347
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.556347
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
17.556347
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
17.556347
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.212812
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.212812
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
18.212812
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
18.212812
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.989788
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.989788
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
18.989788
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
18.989788
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.162033
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.162033
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
19.34324
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.98645
seq distance
23
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
19.98645
seq distance
23
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.774643
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.774643
seq distance
False
chain
A
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
20.950718
seq distance
False
chain
B
In NDI; dbSNP:rs121964893.
original residue
Y
variation residue
H
position
2
score
59.09090909090909
distance
20.950718
seq distance
False
chain
B
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.42519
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.42519
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.439451
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.439451
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
21.439451
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
21.439451
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.051712
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.051712
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.051712
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.051712
seq distance
False
chain
A
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.180563
seq distance
False
chain
D
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
22.180563
seq distance
False
chain
D
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.059698
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.059698
seq distance
False
chain
A
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.732855
seq distance
False
chain
B
In NDI; weakly active; dbSNP:rs142886338.
original residue
P
variation residue
L
position
7
score
59.09090909090909
distance
27.732855
seq distance
False
chain
B
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.033764
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.033764
seq distance
False
chain
A
Details
Redox score
61.23
PDB code
1npo
Structure name
bovine neurophysin ii complex with oxytocin
Structure deposition date
1996-02-01
Thiol separation (Å)
9.75
Half-sphere exposure sum
104
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
58 (Residue 27 in this structure)
Residue number B
105 (Residue 74 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 A 28 A 73
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.7915263
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.7915263
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
2.7915263
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
2.7915263
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.8587544
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.8587544
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.8587544
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.8587544
seq distance
0
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.6878898
seq distance
12
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.6878898
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
3.6878898
seq distance
12
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
3.6878898
seq distance
12
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
3.8968952
seq distance
11
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
3.8968952
seq distance
11
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.21265
seq distance
8
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6543303
seq distance
5
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.6543303
seq distance
5
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.7164435
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
4.7164435
seq distance
1
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.801638
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.801638
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
4.801638
seq distance
7
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
4.801638
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.887357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.887357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.887357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.887357
seq distance
1
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
5.170621
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
5.170621
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
5.170621
seq distance
6
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
5.170621
seq distance
6
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.0676155
seq distance
12
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.2063823
seq distance
7
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
7.2063823
seq distance
7
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.365809
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.365809
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.484917
seq distance
8
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
7.484917
seq distance
8
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.7742805
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.7742805
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.378733
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.378733
seq distance
5
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.378733
seq distance
5
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.378733
seq distance
5
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.342597
seq distance
16
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.342597
seq distance
16
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
9.342597
seq distance
16
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
9.342597
seq distance
16
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.354282
seq distance
17
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
9.354282
seq distance
17
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.141166
seq distance
14
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
10.141166
seq distance
14
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.925673
seq distance
4
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
10.925673
seq distance
4
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.822757
seq distance
11
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
12.822757
seq distance
11
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.98391
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
13.98391
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.573482
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.573482
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
14.573482
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
14.573482
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.783909
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.783909
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
14.783909
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
14.783909
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.835566
seq distance
19
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.835566
seq distance
19
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
14.835566
seq distance
19
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
14.835566
seq distance
19
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.846729
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.846729
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.846729
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.846729
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.239218
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.239218
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
16.239218
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
16.239218
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.437883
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
16.437883
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.754665
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
16.754665
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.17735
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.17735
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.884808
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
17.884808
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.92335
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
17.92335
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.702805
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
19.119633
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
19.119633
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
19.119633
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
19.119633
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.415771
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
19.415771
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.656021
seq distance
22
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
19.656021
seq distance
22
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.334246
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.334246
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
20.334246
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
20.334246
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.38253
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.742714
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.742714
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.742714
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.742714
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.746737
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.746737
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
22.017775
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
22.017775
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.093395
seq distance
22
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
22.093395
seq distance
22
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.096224
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.096224
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
22.096224
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
22.096224
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20754
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.20754
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.708687
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
22.708687
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.074041
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
23.074041
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.090843
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.090843
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.090843
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.090843
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.853397
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.853397
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
23.853397
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
23.853397
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
25.352255
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
25.352255
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
26.781399
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
26.781399
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
26.792896
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
26.792896
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.386969
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
27.386969
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.452915
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.452915
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
29.507532
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
29.507532
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
29.507532
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
29.507532
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
29.78672
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
29.78672
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
30.581203
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
30.581203
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
30.698677
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
30.698677
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
30.698677
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
30.698677
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
30.86165
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
30.86165
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
30.86165
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
30.86165
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.912533
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
30.912533
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
33.114548
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
33.114548
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
34.478985
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
34.478985
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
34.478985
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
34.478985
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
35.27634
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
35.27634
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
35.27634
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
35.27634
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
35.82634
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
35.82634
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
36.093555
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
36.093555
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
36.093555
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
36.093555
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
36.747147
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
38.267445
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
38.267445
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
38.267445
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
38.267445
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
39.280037
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
39.280037
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
39.280037
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
39.280037
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
39.404266
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
39.404266
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
39.579605
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
42.017292
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
42.017292
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
42.88227
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
42.88227
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
43.597393
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
43.597393
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
43.597393
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
43.597393
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
44.016983
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
44.016983
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
45.444798
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
45.444798
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
45.444798
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
45.444798
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
46.113247
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
46.113247
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
46.240246
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
46.240246
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
46.240246
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
46.240246
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
46.483192
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
47.06288
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
47.06288
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
48.047253
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
48.047253
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
48.047253
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
48.047253
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
48.166687
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
48.166687
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
48.198856
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
48.198856
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
48.400043
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
48.400043
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
48.65521
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
48.65521
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
48.65521
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
48.65521
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.127647
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
50.127647
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
50.679886
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
50.679886
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
50.679886
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
50.679886
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
50.987034
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
50.987034
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
50.987034
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
50.987034
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
51.171288
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
51.61234
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
51.61234
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
51.61234
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
51.61234
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
52.663555
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
52.663555
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
54.01056
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
54.01056
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
54.01056
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
54.01056
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
59.248417
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
59.248417
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
62.443974
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
62.443974
seq distance
False
chain
G
Details
Redox score
61.2
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.77
Half-sphere exposure sum
96
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
59 (Residue 28 in this structure)
Residue number B
104 (Residue 73 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 E 34 E 73
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
2.7146795
seq distance
0
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
3.918268
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
4.0054154
seq distance
12
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.0306683
seq distance
11
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
4.0306683
seq distance
11
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
4.0653424
seq distance
8
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.523986
seq distance
1
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.838084
seq distance
5
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
4.838084
seq distance
5
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
5.1115546
seq distance
7
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
5.4900813
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
5.4900813
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
5.4900813
seq distance
6
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
5.4900813
seq distance
6
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1647477
seq distance
False
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.1647477
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1668797
seq distance
7
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
6.1668797
seq distance
7
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.3162026
seq distance
2
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.3162026
seq distance
2
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
7.74283
seq distance
12
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.128711
seq distance
13
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
9.128711
seq distance
13
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.214084
seq distance
14
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
9.214084
seq distance
14
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.080101
seq distance
16
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.080101
seq distance
16
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
10.080101
seq distance
16
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
10.080101
seq distance
16
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.184486
seq distance
11
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.184486
seq distance
11
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
10.184486
seq distance
11
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
10.184486
seq distance
11
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.841219
seq distance
17
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.841219
seq distance
17
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.228499
seq distance
20
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
11.228499
seq distance
20
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.567521
seq distance
10
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
12.567521
seq distance
10
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.619464
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.619464
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.648912
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
13.805992
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.982977
seq distance
17
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
13.982977
seq distance
17
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.650779
seq distance
False
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
14.650779
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.74029
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
15.051
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.929674
seq distance
False
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
15.929674
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.194613
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
16.194613
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.387339
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.387339
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.9806
seq distance
13
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.9806
seq distance
13
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
16.9806
seq distance
13
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
16.9806
seq distance
13
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.908106
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
17.908106
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.092606
seq distance
False
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
18.092606
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
18.330143
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
18.342243
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
19.296556
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
20.249483
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
20.661041
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.709297
seq distance
False
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
20.709297
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
20.773973
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.02584
seq distance
False
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.02584
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
21.419865
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.80576
seq distance
16
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
21.80576
seq distance
16
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.75996
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
23.75996
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.03893
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
24.03893
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.121445
seq distance
17
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
24.121445
seq distance
17
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.297663
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
25.297663
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.112793
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.112793
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
26.112793
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
26.112793
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.61029
seq distance
False
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
26.61029
seq distance
False
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
27.041157
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
27.041157
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.368511
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
28.368511
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
28.639084
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
28.639084
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
29.025198
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
29.025198
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.205795
seq distance
False
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.205795
seq distance
False
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
30.971819
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
30.971819
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
30.971819
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
30.971819
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
31.506958
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
31.506958
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
32.331654
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
32.331654
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
32.331654
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
32.331654
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.461674
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
32.461674
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
32.859425
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
32.859425
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
32.859425
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
32.859425
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
34.655605
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
34.655605
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
36.07879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
36.07879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
36.07879
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
36.07879
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
36.53384
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
36.53384
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
36.53384
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
36.53384
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
37.776306
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
37.776306
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
37.776306
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
37.776306
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
37.83632
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
37.83632
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
38.226803
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
39.571487
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
39.571487
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
39.571487
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
39.571487
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
40.313698
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
40.96719
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
40.96719
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
41.164394
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
41.164394
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
41.164394
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
41.164394
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
43.50096
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
43.50096
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.34869
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
44.34869
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.283257
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.283257
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
45.283257
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
45.283257
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
45.43473
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
45.43473
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.618378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.618378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.618378
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.618378
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
47.939102
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
47.939102
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.02928
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.02928
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
48.02928
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
48.02928
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.900738
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
48.900738
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
49.053005
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
49.536434
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
49.536434
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
49.854366
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
49.854366
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
50.012497
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
50.012497
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
50.012497
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
50.012497
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.04835
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
50.04835
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.23109
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.23109
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
50.23109
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
50.23109
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.23278
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
52.23278
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
52.799313
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
52.799313
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
52.799313
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
52.799313
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
53.092247
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.22196
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.22196
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
53.22196
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
53.22196
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.77888
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.77888
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
53.77888
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
53.77888
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.445
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
54.445
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
55.11514
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
55.11514
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
55.11514
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
55.11514
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
60.38985
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
60.38985
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
63.570015
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
63.570015
seq distance
False
chain
C
Details
Redox score
60.92
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.64
Half-sphere exposure sum
95
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
65 (Residue 34 in this structure)
Residue number B
104 (Residue 73 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
2bn2 G 27 G 79
A redox-regulated disulphide may form within Vasopressin-neurophysin 2-copeptin at these cysteines. However, the redox score of this cysteine pair is lower than any known redox-active disulphide.
Relevent regions
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7876592
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
2.7876592
seq distance
0
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.043247
seq distance
5
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.043247
seq distance
5
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
4.043247
seq distance
5
chain
G
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
4.043247
seq distance
5
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.272046
seq distance
13
chain
G
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
4.272046
seq distance
13
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
4.519911
seq distance
1
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
4.8561354
seq distance
7
chain
G
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
4.8561354
seq distance
7
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.3292847
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
5.3292847
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.049846
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.049846
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
6.049846
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
6.049846
seq distance
6
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.292982
seq distance
9
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
6.292982
seq distance
9
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.72804
seq distance
11
chain
G
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
6.72804
seq distance
11
chain
G
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.2583942
seq distance
False
chain
E
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
7.2583942
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.526879
seq distance
10
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
7.526879
seq distance
10
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.482428
seq distance
4
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.482428
seq distance
4
chain
G
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
8.482428
seq distance
4
chain
G
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
8.482428
seq distance
4
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.82644
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.82644
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
8.82644
seq distance
12
chain
G
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
8.82644
seq distance
12
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.34084
seq distance
13
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.34084
seq distance
13
chain
G
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
9.34084
seq distance
13
chain
G
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
9.34084
seq distance
13
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
9.451883
seq distance
14
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.9050865
seq distance
3
chain
G
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
9.9050865
seq distance
3
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.666976
seq distance
23
chain
G
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
10.666976
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.180736
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.180736
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
11.180736
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
11.180736
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.237026
seq distance
22
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.237026
seq distance
22
chain
G
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
11.237026
seq distance
22
chain
G
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
11.237026
seq distance
22
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.74176
seq distance
17
chain
G
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
11.74176
seq distance
17
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.770214
seq distance
18
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.770214
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
11.770214
seq distance
18
chain
G
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
11.770214
seq distance
18
chain
G
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.813659
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.813659
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
11.813659
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
11.813659
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
12.322224
seq distance
6
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.361199
seq distance
20
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.361199
seq distance
20
chain
G
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
12.361199
seq distance
20
chain
G
In NDI.
original residue
variation residue
position
47
score
100.0
distance
12.361199
seq distance
20
chain
G
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.953433
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
12.953433
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.164467
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.164467
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
13.164467
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
13.164467
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.950796
seq distance
False
chain
E
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
13.950796
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.142643
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.142643
seq distance
False
chain
E
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
14.142643
seq distance
False
chain
E
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
14.142643
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.028367
seq distance
False
chain
E
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
15.028367
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
15.326913
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.482678
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.482678
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
15.482678
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
15.482678
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.799357
seq distance
False
chain
E
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
15.799357
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.33847
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
16.33847
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.385756
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.385756
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
16.385756
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
16.385756
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
16.897333
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.08812
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
17.08812
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
17.226608
seq distance
23
chain
G
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
17.226608
seq distance
23
chain
G
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.28025
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.28025
seq distance
False
chain
E
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
17.28025
seq distance
False
chain
E
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
17.28025
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.005648
seq distance
False
chain
E
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
18.005648
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
18.967064
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
18.967064
seq distance
False
chain
E
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
18.967064
seq distance
False
chain
E
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
18.967064
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
19.135437
seq distance
False
chain
E
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
19.135437
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
20.235521
seq distance
24
chain
G
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
20.235521
seq distance
24
chain
G
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.96587
seq distance
False
chain
E
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
21.96587
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.003857
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.003857
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
22.003857
seq distance
False
chain
E
In NDI.
original residue
variation residue
position
47
score
100.0
distance
22.003857
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.03004
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
27.03004
seq distance
False
chain
E
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.80881
seq distance
False
chain
A
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
28.80881
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.96521
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
28.96521
seq distance
False
chain
A
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.188953
seq distance
False
chain
E
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
29.188953
seq distance
False
chain
E
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.24814
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.24814
seq distance
False
chain
A
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
32.24814
seq distance
False
chain
A
In NDI.
original residue
variation residue
position
47
score
100.0
distance
32.24814
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
32.919415
seq distance
False
chain
A
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
32.919415
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.248257
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
35.248257
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.213985
seq distance
False
chain
A
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
36.213985
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.27283
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
36.27283
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
37.2477
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
37.2477
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
37.838303
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
39.138477
seq distance
False
chain
A
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
39.138477
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
39.685455
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
39.685455
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
39.739704
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
39.739704
seq distance
False
chain
A
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
39.739704
seq distance
False
chain
A
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
39.739704
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
40.805084
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
40.805084
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
40.805084
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
40.805084
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
42.67832
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.744583
seq distance
False
chain
A
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
42.744583
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
43.69429
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
44.86618
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.25229
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.25229
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
45.25229
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
45.25229
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
45.784615
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
45.784615
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
47.127426
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
47.25009
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
47.290966
seq distance
False
chain
A
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
49.561745
seq distance
False
chain
C
In NDI; dbSNP:rs28934878.
original residue
V
variation residue
A
position
36
score
100.0
distance
49.561745
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.911
seq distance
False
chain
A
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
49.911
seq distance
False
chain
A
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
53.37143
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
14
score
100.0
distance
53.37143
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
53.62752
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
53.62752
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
28
score
90.9090909090909
distance
53.62752
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
28
score
90.9090909090909
distance
53.62752
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
54.115593
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
27
score
90.9090909090909
distance
54.115593
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
54.91026
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
54.91026
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
F
position
73
score
90.9090909090909
distance
54.91026
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
73
score
90.9090909090909
distance
54.91026
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
55.707386
seq distance
False
chain
C
In NDI.
original residue
A
variation residue
P
position
68
score
90.9090909090909
distance
55.707386
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
55.741177
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
55.741177
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
74
score
90.9090909090909
distance
55.741177
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
Y
position
74
score
90.9090909090909
distance
55.741177
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI; strong accumulation in the endoplasmic reticulum and an altered morphology of this organelle; dbSNP:rs74315383.
original residue
C
variation residue
G
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
W
position
85
score
54.54545454545454
distance
55.804947
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
57.61654
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
57.61654
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
G
position
67
score
90.9090909090909
distance
57.61654
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
67
score
90.9090909090909
distance
57.61654
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
57.818768
seq distance
False
chain
C
In NDI; dbSNP:rs121964883.
original residue
G
variation residue
V
position
17
score
100.0
distance
57.818768
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
58.38571
seq distance
False
chain
C
In NDI.
original residue
P
variation residue
L
position
24
score
90.9090909090909
distance
58.38571
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
58.567627
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
R
position
21
score
100.0
distance
58.567627
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
58.567814
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
58.567814
seq distance
False
chain
C
In NDI; dbSNP:rs121964888.
original residue
G
variation residue
R
position
23
score
100.0
distance
58.567814
seq distance
False
chain
C
In NDI; dbSNP:rs121964887.
original residue
G
variation residue
V
position
23
score
100.0
distance
58.567814
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
58.643215
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
20
score
100.0
distance
58.643215
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.034157
seq distance
False
chain
C
In NDI; dbSNP:rs121964885.
original residue
G
variation residue
W
position
62
score
90.9090909090909
distance
59.034157
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.12412
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.12412
seq distance
False
chain
C
In NDI.
original residue
C
variation residue
S
position
61
score
90.9090909090909
distance
60.12412
seq distance
False
chain
C
In NDI; dbSNP:rs121964891.
original residue
C
variation residue
Y
position
61
score
90.9090909090909
distance
60.12412
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
60.32245
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
60.32245
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
C
position
66
score
95.45454545454545
distance
60.32245
seq distance
False
chain
C
In NDI.
original residue
R
variation residue
P
position
66
score
95.45454545454545
distance
60.32245
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
C
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
D
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI; dbSNP:rs121964886.
original residue
G
variation residue
V
position
65
score
86.36363636363636
distance
60.583385
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
61.66931
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
61.66931
seq distance
False
chain
C
In NDI.
original residue
G
variation residue
R
position
57
score
90.9090909090909
distance
61.66931
seq distance
False
chain
C
In NDI; dbSNP:rs121964882.
original residue
G
variation residue
S
position
57
score
90.9090909090909
distance
61.66931
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
62.676807
seq distance
False
chain
C
In NDI; dbSNP:rs121964890.
original residue
S
variation residue
F
position
56
score
90.9090909090909
distance
62.676807
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
64.21133
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
64.21133
seq distance
False
chain
C
In NDI.
original residue
E
variation residue
G
position
47
score
100.0
distance
64.21133
seq distance
False
chain
C
In NDI.
original residue
variation residue
position
47
score
100.0
distance
64.21133
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
69.554214
seq distance
False
chain
C
In NDI.
original residue
L
variation residue
P
position
50
score
100.0
distance
69.554214
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
72.61008
seq distance
False
chain
C
In dbSNP:rs5195.
original residue
P
variation residue
L
position
51
score
100.0
distance
72.61008
seq distance
False
chain
C
Details
Redox score
60.75
PDB code
2bn2
Structure name
crystal structure of bovine neurophysin ii complexed with the vasopressin analogue phe-tyr amide
Structure deposition date
1998-12-18
Thiol separation (Å)
9.99
Half-sphere exposure sum
100
Minimum pKa
nan
% buried
nan
Peptide accession
P01180
Residue number A
58 (Residue 27 in this structure)
Residue number B
110 (Residue 79 in this structure)
Peptide name
Vasopressin-neurophysin 2-copeptin
If this tool was useful for finding a disulphide, please cite: